Wound healing - Tissue mediators Flashcards
1
Q
PDGF
A
- Secreted by activated platelets and macrophages
- Induces vascular remodeling and smooth muscle cell migration
- Stimulates fibroblast growth for collagen synthesis
2
Q
FGF
A
Stimulates angiogenesis
3
Q
EGF
A
Stimulates cell growth via tyrosine kinases (EGFR/ErbB1)
4
Q
TGF-β
A
Angiogenesis, fibrosis, cell cycle arrest
5
Q
Metalloproteinases
A
Tissue remodeling
6
Q
VEGF
A
Stimulates angiogenesis