PHASE Of WOUnD HEALInG

Question 1

Inflammatory (up to 3 days after wound)

Answer 1

Platelets, neutrophils, macrophages

Clot formation, INC vessel permeability and neutrophil migration into tissue

macrophages clear debris 2 days later

Question 2

Proliferative (day 3–weeks after wound)

Answer 2

Fibroblasts, myofibroblasts, endothelial cells,
keratinocytes, macrophages

Deposition of granulation tissue and type III collagen, angiogenesis, epithelial cell
proliferation, dissolution of clot, and wound contraction (mediated by myofibroblasts)

Question 3

Remodeling (1 week–6+ months after wound)

Answer 3

Fibroblasts

*Type III collagen replaced by *type I collagen, INC tensile strength of tissue