wound healing Flashcards
goal is minimize bleeding and create barrier from contamination
MOA: Localized vasoconstriction, activation of platelets
WHAT PHASE OF WOUND HEALING
hemostasis
goal = Restoration of vascular integrity, formation of connective tissue, wound contraction, reepithelialization
MOI: Fibroblasts granulation tissue
WHAT PHASE OF WOUND HEALING
proliferation
Goal: Control bioburden, establish clean wound bed
MOA: Localized vasodilation, inc tissue permeability bring exudate to wound, localized response in proportion to injury
WHAT PHASE OF WOUND HEALING
inflammation
Immature collagen organized into mature collagen
Scar tissue only up to 80% or original tissue strength
Lacks elastin, stiffer than original tissue
WHAT PHASE OF WOUND HEALING
remodeling