Wound Care Key Points Flashcards
Sublethal injury
Alters function without causing cell death
Lethal injury
An irreversible process that causes cell deaths
What is common in cublethal injuries
Cell adaptations
-part of many normal physiological processes
Hypertrophy
Increase in the size of cells
-resulting in increased tissue mass without cell division
Hyperplasia
Increase in number of cells
-resulting from increased cellular division
-reversible when stimulus is removed
Atrophy
Decrease in size of tissue or organ
-caused by decrease number of cells or reduction in the size of individual cells
Metaplasia
Transformation of one cell type into another
-in response to a change in physiological condition or an external irritant
Dysplasia
Abnormal differentiation of dividing cells that results in changes in their size, shape, appearance
Anaplasia
Cell differentiation to a more immature or embryonic form
Examples of individual cell death in normal situations
Skin, gut epithelium and embryogenesis
Apoptosis
Programmed cell death
-human health dependant on this process
When is cell death not a normal event
In developed tissues such as brain, liver, necrosis
Inflammatory response
Sequential reaction to cell injury
-neutralizes and dilutes inflammatory agent
-removes necrotic materials
-creates healing environment
The inflammatory response can be divided into
Vascular, cellular, formation and healing
-responses
Vascular response
Results in vasodilation causing hyperaemia which raises filtration pressure
-increased blood flow in the area
Cellular response
Neutrophils and monocytes move to the inner surface of the capillaries and then through capillary wall to site of injury
Exudate
Consists of fluid, leukocytes that move from the circulation to the site of injury
Nature and quantity of exudate depend on
Type and severity of the injury and tissues involved
Healing includes two major components
Regeneration and repair
Regeneration
Replacement of lost cells and tissues with cells of the same type
Repair
More common type of healing, results in scar formation
Primary intention
Healing takes place when wound margins are neatly approximated as in surgical incision or a paper cut