Word Associations Flashcards

1
Q

dorsal striatum

A

binge / intoxication area of brain
habit

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2
Q

nucleus accumbens

A

binge / intoxication area of brain
REINFORCEMENT
ventral striatum
core of NA, pleasure

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3
Q

ventral tegmental area (VTA)

A

binge / intoxication area of brain
DOPAMINE
REWARD
substantia nigra

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4
Q

hippocampus

A

preoccupation / anticipation area of brain
with amygdala = LEARNING/MEMORY with emotional context (ex. cravings occur based on specific memory and conditioned withdrawal)

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5
Q

anterior cingulate cortex

A

preoccupation / anticipation area of brain

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6
Q

prefrontal cortex

A

preoccupation / anticipation area of brain: ACC & hippocampus
last part of brain to develop in youth

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7
Q

amygdala

A

withdrawal area of brain
with hippocampus = LEARNING/MEMORY with emotional context (ex. cravings occur based on specific memory and conditioned withdrawal)

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8
Q

basal/bed nucleus of stria terminalis

A

withdrawal area of brain

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9
Q

what specific type of endocarditis is highly associated with IVDU

A

tricuspid valve endocarditis (right sided heart endocarditis)

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10
Q

flumazenil

A

TREATMENT for BZD OD, reverses BZD sedation

contraindicated if other substances because likely to INDUCE SEIZURE

INHIBITS GABA-A ligand gated chloride ion channel

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11
Q

phenelzine

A

MAOI - when in combo with any serotonin med - serotonin syndrome

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12
Q

funky chicken / tweaking

A

chronic methamphetamine use leads to choreiform / parkinsonian movements

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13
Q

z drugs

A

BZD-like effects, not detectable in UDS
zolpidem, zopiclone, zolepon
schedule V

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14
Q

confabulation

A

seen in KORSAKOFF syndrome
confabulations can be spontaneous or provoked

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15
Q

anabolic steroids –> cancer

A

benign hepatic neoplasm formation –> hepatocellular cancer

can provide B1/B6/B12/linoleic acid/nicotinamide to help prevent

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16
Q

cocaine in pregnancy

A

baby: placental abruption, neonatal intracranial bleeds, low birthweight, prematurity, low head circumference

mother: HTN emergency, seizure, migraine

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17
Q

nystagmus

A

PCP - NMDA receptor antagonist
rotary nystagmus is pathognomonic to PCP

18
Q

conjunctival injection

A

THC

19
Q

tx for AUD in decompensated cirrhosis

A

acamprosate

20
Q

increase in delta FosB

A

EtOH withdrawal

21
Q

hyperthermia causing death

A

in amphetamine (ex. phentermine) overdose

22
Q

naloxone challenge

A

0.1mg (30min) 0.2mg (30min) 0.4mg
if no AEs, ok to administer naltrexone

23
Q

labs that indicate anabolic steroid use

A

ELEVATION: Hgb/Hct, LDL
LOW: sperm count, HDL, LH, sex hormone

24
Q

MPTP

A

substance made accidentally when trying to produce merperidine
leads to EXTREME RIGID MVMT/parkinsonian to paralysis “can’t move” toxicity seen in ER setting, may mention chemistry graduate student that does recreational drugs

25
Q

hypersexual

A

cathinone intoxication

26
Q

bruxism, jaw clenching, restless legs

A

ectasy (MDMA)

27
Q

hep C renal disease

A

membranoproliferative glomerulonephritis w/ or w/o mixed cryoglobulinemia (normal C3, elevated C4)

dx include hematuria, hypertension, proteinuria

28
Q

mitragynine

A

kratom, partial mu agonist, antagonist at delta and kappa opioid receptor

29
Q

repetitive movements

A

seen in amphetamine intoxication (tx with bzd)

30
Q

suddenly awakens to baseline even if intubated

A

GHB toxicity

31
Q

specific type of kidney injury in inhalant toxicity

A

renal tubular acidosis, hypokalemia

32
Q

exogenous pigments, hands and face

A

inhalation of volatile hydrocarbons

33
Q

insula

A

part of brain that helps identify hunger/thirst/hot/cold stimuli and have emotional response

34
Q

OFC

A

REWARD processing area of brain that brings meaning to specific action (ex. video game accomplishment = accomplishment on anything/test)

35
Q

false positive THC screen by…

A

pantoprazole (PPI)

36
Q

hematuria

A

ketamine cystitis

37
Q

DSM Criteria for UD

A

C cut down, unsuccessful
H hazardous use
E excessive use
W withdrawal
T time increased using/recovering, finding
H health effects
A activities changed
T tolerance
C cravings
O obligations lost to drug
P personal problems/family
2-3 mild, 4-5 mod, >6 severe

38
Q

specific marker for recent ETOH use

A

CDT - carbohydrate deficient tranferrin

39
Q

enteroceptive

A

mood states that precipitate substance use

with exteroceptive = cues and priming

40
Q

exteroceptive

A

environment to senses (smelling/seeing substance)

with enteroceptive = cues and priming