Wk5 Flashcards
Neurons
Generate electricity and create nerve impulses and release chemicals that facilitate communication.
Glial cells
Are the support of neurons, they; hold neurons in place, manufacture nutrient chemicals and absorb toxins and waste.
3 steps in the activation of nerve impulses
- neuron has resting electric potential
- action potential occurs when neuron is stimulated
- original iconic balance is restored; neuron is at rest again
Absolute refractory period
neuron cannot fire again until it regains its natural negative polarisation
All-or-none law
action potentials occur at a uniform and maximum potential or they do not occur at all
Action potential threshold
Change needed to fire is 250 milivolts
Graded potentials
any change to resting potential that doesn’t reach the threshold.
4 steps of neuron communication
- synthesis - transmitter molecules are formed
- storage - transmitter molecules are stored in the axon terminals
- Release - action potential in one neuron triggers the release of those transmitter molecules across the gap
- Binding - transmitter molecules bind themselves to receptor sites which are large protein molecules embedded in the receiving neurons cell membrane.
What are the 2 types of neurotransmitters?
Excitatory - cause the action potential to fire
Inhibitory - prevent the neuron from firing
3 types of neurons
Sensory neurons - carry messages from the sense organs to the spinal cord and brain
Motor neurons - transmit impulses from the brain and spinal cord to the muscles and organs
Interneurons - perform connective or associate functions
Excitatory neurons
Cause the action potential to fire
Inhibitory neurons
Prevent the neuron from firing
Sensory neurons
Carry messages from the sense organs to the spinal cord and brain - outside-in.
Motor neurons
Transmit impulses from the brain and spinal cord to the muscles and organs - inside-out.
Interneurons
Perform connective functions
Acetylcholine
Learning and memory. Disorders - Alzheimer’s (under), paralysis (under), convulsions (over).
noradrenalin
Excitatory - Controls learning, memory, wakefulness and eating. Disorders - Depression (under), stress and panic (over)
Serotonin
Inhibitory - Mood, sleep, eating and arousal - underlies pleasure and pain. Disorders - Depression, sleep and eating disorders (under) and OCD (over).
Dopamine
Excitatory - voluntary movement, emotional arousal, learning, memory and experiences of pleasure/pain. Disorders - Parkinsons and depression (under) and schizophrenia (over)
GABA
Inhibitory
Endorphins
Mood and pain. Disorders - Insensitivity to pain (over) Pain hypersensitivity (under)
Dendrites
Branch like extensions of the neuron that receive inputs from other cells.
Cell body
Includes the nucleus that contains the genetic material of the cell and is considered the brains of the operation.
Axon
Long extension from the cell body (up to 1mtre) that transmits information to other neurons.
Myelin sheath
coat of cells composed primarily of fats that help transmit information to other neurons. Insulates axon from chemical and physical stimuli that might interfere with nerve impulses. They also dramatically increase the speed of transmission.
White matter
From the myelinated axons
Grey matter
Cell bodies, dendrites and unmyelinated sheaths
Terminal buttons
At the end of the axon sending signals from a neuron to adjacent cell.
Synaptic cleft
Space between two cells
Synapses
Connections between neurons
Resting potential
When a neuron is not firing and electrical charge is 70 milivolts. Membrane is polarised - inside has a negative change and outside has a positive charge.