Whooping Cough Flashcards

1
Q

Whooping cough is an highly contagious respiratory tract infection, but what is the incidence?

1 - 2000 per 100,000
2 - 200 per 100,000
3 - 20 per 100,000
4 - 2 per 100,000

A

4 - 2 per 100,000

Equally likely in males and females

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Is the whooping cough more common in adults or children?

A
  • children

Most common in infants

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What organism is responsible for causing whooping cough?

1 - Bordetella pertussis
2 - Influenza
3 - Adenovirus
4 - Streptococcus pneumoniae

A

1 - Bordetella pertussis

Whooping cough can also be called Pertussis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Which of the following is NOT a risk factor for contracting whooping cough/pertussis?

1 - Immunocompromised/unvaccinated
2 - Age (unvaccinated infants
3 - Exposure to infected individuals
4 - Pregnant women transmit to foetus in 3rd trimester
5 - Gender (females more likely)
6 - Co-morbidities

A

5 - Gender (females more likely)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

All of the following are common clinical signs of whooping cough, but what is the tell tale sign that will normally confirm the diagnosis?

1 - acute cough lasting >14 days
2 - inspiratory whooping cough
3 - 2-3 days of coryzal symptoms
4 - post-tussive vomiting

A

2 - inspiratory whooping cough

In severe cases:

  • coughing can cause subconjunctival haemorrhages
    or anoxia leading to syncope & seizures
  • clinical symptoms may last as long as 10-14 weeks
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Although the inspiratory whoop is the hall mark of the whooping cough, does it always have to be present to be diagnosed?

A
  • no

The inspiratory whoop is due to inspiration against a closed glottis due to the infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Are the bouts of coughing in the whooping cough worse during the day or evening?

A
  • Usually worse at night and after feeding

May be following by vomitting due to excessive coughing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Although diagnosis is often clinical, what is the best marker for whooping cough in the blood?

1 - creatine kinase
2 - CRP
3 - raised lymphocytosis
4 - macrophages

A

3 - raised lymphocytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Although diagnosis is often clinical, what is now the most common form of diagnosing patients with whooping cough?

1 - PCR and serology
2 - blood culture and chest-X-ray
3 - throat examination and chest X-ray
4 - serology and urinalysis

A

1 - PCR and serology

Typically following a swab of the nasal canals, but can take weeks to get results

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Is the management of whooping cough typically just supportive or supportive with antibiotics?

A

Supportive with antibiotics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

All of the following are macrolids, which is typically the 1st line therapy in whooping cough if the cough began in <21 days. Which of the following is NOT a macrolid?

1 - clarithromycin
2 - azithromycin
3 - gentamicin
4 - erythromycin

A

3 - gentamicin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Hospitalisation is not always required in whooping cough, but which of the following would be an indicator for admission?

1 - age <18 months
2 - cough with vomiting
3 - age <6 months
4 - temperature >38 degrees

A

3 - age <6 months

May require additional supportive care measures like oxygen supplementation, fluid management and nutritional support.

Also important to reduce the risk of complications

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Do all household members and close contacts require prophylactic antibiotic therapy?

A
  • Yes

This is irrespective of vaccination status.

Antibiotics should be in the form of a macrolid (azithromycin, clarithromycin or erythromycin)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the most effective management of whooping cough?

1 - hand washing
2 - disposing of used tissues
3 - vaccination
4 - antibiotics

A

3 - vaccination

ALWAYS ask vaccination status

Typically given as part of the 6 in 1 at 8, 12 and 16 weeks, and 3-5 years

Pregnancy women can get it between 20 and 32 weeks, provides form of passive immunisation to the baby before it can be vaccinated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Which if the following is NOT a complication of the whooping cough?

1 - subconjunctival haemorrhage
2 - pneumonia
3 - bronchiectasis
4 - seizures
5 - liver cirrhosis

A

5 - liver cirrhosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly