Breast abscess/ mastitis Flashcards
When a patient has suspected breast pathophysiology they will attend a specialist breast clinic. The basis of all breast investigations can be remembered using CRP. What does this relate to?
1 - clinical examination, relative history, path medical history
2 - clinical examination, radiology, pathology
3 - clinical examination, radiology, path medical history
4 - clinical examination, relative history, pathology
2 - clinical examination, radiology, pathology
- referred to as the triple assessment if lump is present
When a patient has suspected breast pathophysiology they will attend a specialist breast clinic. During the clinical examination and history we ask about pain, and if it is cyclic or non cyclic. What does this mean?
1 - cyclic refers to pain that comes and goes in continuous pattern
2 - patient that cycles in line with circadian rhythm
3 - pain that is present during menstruation cycle
3 - pain that is present during menstruation cycle
- so non-cyclic pain is anything not involving menstruation
We must ask questions relating to oestrogen exposure. One question is what age were you during menarche. What is this?
1 - when your periods stopped
2 - when you began contraception
3 - when periods stopped for >6 months
4 - when they had their 1st period
4 - when they had their 1st period
- menopause is the opposite, so when did periods stop
If we locate a mass on the breasts, we must describe all of the following, EXCEPT?
1 - location
2 - size
3 - contour
4 - texture
5 - duration its been there
5 - duration its been there
Patients of a certain age will require a mammogram screening every 3 years at what age?
1 - >40
2 - >50
3 - >60
4 - >70
3 - >60
- NHS states that it is between 51-71 years of age
- stops at age 71
Why do patients <40 y/o not routinely get a mammogram in the UK?
1 - too expensive
2 - women don’t want it
3 - breast tissue is too dense
3 - breast tissue is too dense
- sensitivity in <40 = 50%
- sensitivity in >40 = 95%
What % of breast cancers are missed on routine population screening with mammograms?
1 - 0.5%
2 - 5%
3 - 15%
4 - 50%
2 - 5%
Mammograms are the mainstay for diagnosing breast abnormalities. However, which imaging modality is used to differentiate a breast cyst from a soft tissue mass?
1 - ultrasonography
2 - CT
3 - MRI
4 - Pet scan
1 - ultrasonography
- also 1st line for image guided axillary guided biopsy
Although not commonly used, when can an MRI be useful for imaging breast tissue?
1 - older patients
2 - younger patients
3 - patients with breast implants
4 - patients with pace makers
3 - patients with breast implants
- good at differentiating recurrent breast cancer from scar tissue
As part of the CRP (clinical examination/history, radiology, pathology) patients may receive a core biopsy. This is performed with 2 aids, what are they?
1 - image guided and a nurse assisting
2 - nurse assisting and vacuum biopsy
3 - image guided with vacuum
3 - image guided with vacuum
- imaging is via ultrasound
- vacuum removes and collects biopsy
A core biopsy allows full assessment of any located membranes can also be used to distinguish between carcinoma in-situ and invasive carcinoma. What does carcinoma in-situ mean?
1 - cancer has spread inside the breast
2 - cancer has spread to nearby organs
3 - localised in breast and not beyond the basement membrane
3 - localised in breast and not beyond the basement membrane
Once a core biopsy is taken, where will it be taken?
1 - cytology
2 - histology
3 - biochemistry
4 - bloods
1 - cytology
- allows analysis of cells to identify if malignant
In addition to analysing if the biopsy is carcinoma in situ or invasive, we can also look at molecular markers. Which of the following is NOT a common marker looked for in breast biopsy?
1 - human epidermal growth factor receptor 2 (HER-2) receptors
2 - cancer antigen 19-9 (CA19-9) receptors
3 - estrogen receptors
4 - progesterone receptors
2 - Cancer antigen 19-9 (CA19-9) receptors
- if these come back positive then this is good as we can treat with immunotherapy
What is a cyst?
1 - pus filled collection lined by any type of cell
2 - fluid filled area lined by granulation tissue
3 - fluid filled area lined by epithelial cells
3 - fluid filled area lined by epithelial cells
What % of women will experience breast pain at some point?
1 - 0.7%
2 - 7%
3 - 37%
4 - 70%
4 - 70%
Breast pain can be categorised into various types. Which of the following is most common?
1 - cyclical
2 - non-cyclical
3 - extra-mammary
4 - intra-mammary
3 - extra-mammary
- essentially not breast related
- outside of breast tissue
Cyclical breast pain resolves in what % of women?
1 - 0.2-0.3%
2 - 2-3%
3 - 20-30%
4 - 40-60%
3 - 20-30%
- recurrence is high at 60%
Non-cyclical breast pain does not respond well to therapy, but what % resolves spontaneously?
1 - 0.5%
2 - 5%
3 - 50%
4 - 100%
3 - 50%