White Tissue Lesions (Non-malignant) I Flashcards

1
Q

Which of the following is an acquired lesion that cannot be scraped off?

A) Lupus erythematous
B) Pseudomembranous candidiasis
C) Superficial oral burn
D) White sponge nevus

A

A

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2
Q

Which is not a common site for oral leukoplakia?

A) Buccal mucosa
B) Floor of mouth
C) Hard palate
D) Retromolar area

A

C

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3
Q

A patient presents in the clinic with a gray-white appearance on the buccal mucosa which does not rub off as shown in the picture. Upon closer examination, the lesion diminishes on stretching the cheek. What is the most likely diagnosis?

A) Erythema migrans
B) Leukoedema
C) Morsicatio mucosae oris
D) Oral candidiasis

A

B

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4
Q

Which of the following is not an etiology of oral leukoplakia?

A) Tobacco use
B) Areca nut use
C) Chemotherapy
D) Alcohol consumption

A

C

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5
Q

What is not a prominent feature of epithelial dysplasia?

A) Cellular pleomorphism
B) Drop-shaped rete processes
C) Keratinised single cells
D) Single stratified epithelium layer

A

D

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6
Q

Histopathology shows finger-like processes of proliferating stratified squamous epithelium supported by thin cores of vascular connective tissue showing hyperkeratosis. What is the likely diagnosis?

A) Erythroplakia
B) Leukoplakia
C) Squamous papilloma
D) Verruca vulgaris

A

C

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7
Q

Patient has a solitary, unilateral white lesion on buccal mucosa. Lesion is non-wipeable. Patient is unaware of it, has no known medical history and no known drug allergy. What is the likely diagnosis?

A) Leukoplakia
B) Lichen planus
C) Morsicato
D) Pseudomembranous candidosis

A

A

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8
Q

Which patient has the highest risk of developing leukoplakia?

A) Asthmatic male who is a non-smoker
B) Elderly man who chews betel nut regularly
C) Middle aged female born with cleft lip and cleft palate
D) Young female who drinks alcohol occasionally

A

B

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9
Q

Which of the potentially premalignant oral epithelial lesions has the highest malignant transformation rate?

A) Erythroplakia
B) Erythroleukoplakia
C) Leukoplakia
D) Oral submucous fibrosis

A

A

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10
Q

(Refer to document for picture of squamous papilloma)

A
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11
Q

Which of the following is not a feature of epithelial dysplasia?

A) Loss of polarity of basal cells
B) Presence of only one layer of cells having basaloid appearance
C) Increased nuclear-cytoplasmic ratio
D) Irregular epithelial stratification

A

B (should be more than one)

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12
Q

A patient is diagnosed with Oral Leukoplakia. All of the following findings could have led to this diagnosis except…?

A) Presence of a predominantly red lesion
B) The lesion cannot be wiped off from the oral mucosa
C) The lesion is found on the buccal mucosa
D) The patient consumes alcohol frequently

A

A

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13
Q

(Refer to document for image of oral lichen planus)

Which of the following is a histopathological finding of the above condition?

A) Infiltrate of predominantly B lymphocytes in lamina propria
B) Overgrowth of basal cell layer of epithelium
C) Pointed, “saw-toothed” rete ridges
D) Presence of dysplasia

A

C

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14
Q

Which of the following questions does not help to differentiate between leukoplakia and leukodema before biopsy?

A) Does it disappear on stretching the cheek?
B) Can it be scraped off?
C) Is it congenital or acquired?
D) Is it always benign?

A

B

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15
Q

Which of these present as a finger-like process of proliferating stratified squamous epithelium?

A) Erythroplakia
B) Lichen planus
C) Squamous papilloma
D) Oral leukoplakia

A

C

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16
Q

Which of the following is false regarding the characteristic histological presentation of oral lichen planus?

A) Band-like infiltrate of predominantly T lymphocytes in the lamina propria
B) Epithelial dysplasia present
C) Liquefactive degeneration of basal cell layer of epithelium
D) Pointed, saw-toothed rete ridges

A

B

17
Q

Which of the following is false about oral leukoplakia?

A) Diagnosis should be confirmed with a biopsy
B) It can be linked to tobacco use
C) It has a distinct histological appearance
D) It is a non-wipeable lesion

A

C

18
Q

Which of the following statements correctly describes squamous papilloma?

A) It is a malignant disease
B) It presents as a single warty pedunculated growth at intra oral sites
C) It is more commonly seen in middle aged males
D) It has HPV subtypes of 2 and 4

A

B

19
Q

Which of these is not a PPOELs (Potentially Pre-Malignant Oral Epithelial Lesion)

A) Leukoplakia
B) Erythroplakia
C) Lichen Planus
D) Verrucous carcinoma

A

D

20
Q

Which of the following is false about the management of Oral Leukoplakia?

A) Removal of dysplastic tissue
B) Biopsy is performed for determining the presence and extent of cellular changes
C) Smoking cessation
D) Antibiotics

A

D

21
Q

Which of the following are the proper steps for managing a clinical case of leukoplakia?

A) Histopathological examination of dysplasia > removal of dysplastic tissue > inform patients of risk factors > long term clinical follow up
B) Removal of dysplastic tissue > histopathological examination of ° of dysplasia > inform patients of risk factors > long term clinical follow up
C) Removal of dysplastic tissue > inform patients of risk factors > histopathological examination of ° of dysplasia > long term clinical follow up
D) Inform patients of risk factors > histopathological examination of ° of dysplasia > removal of dysplastic tissue > long term clinical follow up

A

A

22
Q

Which of the following statements is false regarding oral leukoplakia?

A) It has the same predisposing factors as squamous cell carcinoma
B) It is diagnosed clinically and histologically
C) It occurs predominantly in females
D) Its prevalence increases with age

A

C

23
Q

Which one of the following lesions is potentially premalignant?

A) Lichen planus
B) Linea alba
C) Squamous papilloma
D) Verruca vulgaris

A

A

24
Q

Which of the following statements is false?

A) Candida albicans causes oral leukoplakia.
B) Nutritional deficiency causes oral leukoplakia.
C) Oral leukoplakia is more common in males than females.
D) Oral leukoplakia is less common than erythroplakia.

A

D

25
Q

Which of the following is not a histopathologic feature of oral lichens planus?

A) Intense band like chronic inflam infiltrate of T cells in lamina propria
B) Liquefactive degeneration of basal layer
C) Mild hyperkeratosis of surface epithelium
D) Tubular shape fungal hyphae stained magenta by PAS

A

D

26
Q

Which of the following is not a characteristic of Erythroplakia?

A) Common sites include the buccal mucosa, soft palate, tongue, gingiva
B) Has the highest malignant transformation rate among PMDs
C) Treatment of choice is surgical excision
D) Usually affects middle age to elderly

A

A

27
Q

A patient presents with a red lesion on the soft palate of the oral mucosa. Patient complains of recurrent lesions over time and has a surgical excision planned as treatment. What condition does the patient have?

A) Oral Leukoplakia
B) Oral Erythroplakia
C) Lichen Planus
D) Oral Submucous Fibrosis

A

B

28
Q

Which of the following is NOT a characteristic histological feature of oral lichen planus?

A) Cellular pleomorphism
B) Liquefactive degeneration of the basal cell layer
C) Saw-tooth-like rete pegs
D) Subepithelial band of lymphocytes and histiocytes

A

A

29
Q

Which is a feature of carcinoma in situ?

A) Hyperchromatic nuclei
B) Enlarged and multiple nucleoli
C) Mitoses
D) All of the above

A

D

30
Q

Which of the following is NOT a feature of epithelial dysplasia?

A) Drop-shaped rete processes.
B) Increased nuclear-cytoplasmic ratio.
C) Loss of polarity of the basal cells.
D) Nuclear karyolysis.

A

D

31
Q

What is false about oral leukoplakia?

A) It affects the younger population most commonly.
B) It can be caused by tobacco use and alcohol.
C) It is commonly found on the buccal mucosa.
D) It is managed through the removal of dysplastic tissue.

A

A

32
Q

Which of the following is not a risk factor for the malignant transformation of leukoplakia into squamous cell carcinoma?

A) Being located on the floor of mouth
B) Idiopathic leukoplakia
C) Male gender
D) Presence and degree of dysplasia

A

C

33
Q

Which of the following is not a feature of epithelial dysplasia?

A) Increase in polarity of basal cells
B) Drop-shaped rete processes
C) Keratinisation of single cells or cell groups
D) Increased nuclear-cytoplasmic ratio

A

A

34
Q

A patient has a soft tissue lesion. The dentist diagnosed it as oral leukoplakia, which of the following could have led the dentist to diagnosing it as so?

A) The lesion was wipeable and was a predominantly red lesion
B) The lesion was wipeable and was a predominantly white lesion
C) The lesion was non-wipeable and was predominantly a white lesion
D) The lesion was was non-wipeable and was predominantly a red lesion

A

C

35
Q

Which of the following is true of leukoplakia?

A) Leukoplakia can exist in a non-homogenous form
B) Leukoplakia comes off when scraped
C) Leukoplakia is usually diagnosed histologically
D) Leukoplakia occurs less frequently than erythroplakia

A

A

36
Q

Patient comes ito your clinic complaining of a white lesion on the anterior buccal mucosa. Upon clinical examination, you noticed that the white plaque cannot be removed. You decided to swab the area and culture it, on which you notice multiple hyphae. What would be an appropriate first management option?

A) Excise the white spot lesion
B) Prescribe topical anti-fungal
C) Refer to oral medicine
D) Prescribe antibiotics

A

B