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OMOPOR > Malignant Disorders > Flashcards

Malignant Disorders Flashcards

1
Q

Which of the following is true about osteosarcoma?

Associated with Down syndrome
More common in the mandible
Most common primary benign tumour of bone
Occurs at puberty

A

More common in the mandible

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2
Q

Which of the following conditions should be treated with radiotherapy?

Ameloblastoma
Fibrous dysplasia
osseous dysplasia
squamous cell carcinoma

A

squamous cell carcinoma

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3
Q

Which of the following is not a possible radiographic feature of intraosseous squamous cell carcinoma of the jaws?

Root resorption of teeth
Radiolucent mass with epicentre within bone
Widening of PDL, loss of lamina dura
Teeth appear to be “floating in space”

A

Root resorption of teeth

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4
Q

Which of the following is a radiographic feature of osteosarcoma?

Loss of cortical crypts of developing teeth
More common in maxilla than mandible
Sunray pattern suggesting periosteal reactions
Well-defined and non-corticated

A

Sunray pattern suggesting periosteal reactions

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5
Q

Malignant tumours usually present with ill-defined borders which can be observed on radiographs. Which of these malignancies are most likely to present with well-defined borders?

Multiple myeloma
Squamous cell carcinoma
Osteosarcoma
Lymphoma

A

Multiple myeloma

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6
Q

A patient complains of a “hole in his gums” 6 months after extraction of his lower left second molar. The tooth was extracted as it was extremely mobile with very deep probing depths. Radiographic examination reveals a non-healing socket where the tooth was extracted. A radiolucent lesion extending from the socket to the mesial of the #35 was noted. The lesion was ill-defined, non-corticated and irregular. What is the most likely diagnosis?

Osteosarcoma
Osteomyelitis
PA granuloma
SCC

A

SCC

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7
Q

A DPT is taken for Mr Ng, and he presents with a teeth “floating in space appearance”. What is this patient most likely suffering from?

Multiple Myeloma
Periodontal Disease
Osteosarcoma
Squamous Cell Carcinoma

A

Squamous Cell Carcinoma

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8
Q

A 57-year-old male patient presents with a history of heavy smoking for the past 30 years and a long-standing habit of betel nut chewing. He complains of persistent pain in the lower mandibular region. Clinical examination reveals an ulcerated white lesion with raised borders. Cytological analysis of a biopsy specimen shows hyperchromatic nuclei, increased nuclear-to-cytoplasmic ratio, and abnormal keratinization. Radiographically, the lesion appears as an irregularly shaped radiolucent area with ill-defined borders and cortical destruction. Which of the following conditions is most likely indicated by these findings?

Squamous cell carcinoma
Ameloblastoma
Osteosarcoma
Odontogenic keratocyst

A

Squamous cell carcinoma

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9
Q

Which is not a general radiographic feature of malignancy?

Non-corticated border
“Floating teeth”
Regular shape, well-defined border
Destruction of follicle, tooth displacement

A

Regular shape, well-defined border

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10
Q

Which of the following correctly describes the radiographic feature of osteosarcoma?
Intact lamina dura
Corticated borders
Well-defined border
Radiolucent, mixed or radiopaque

A

Radiolucent, mixed or radiopaque

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11
Q

A sunray appearance on a radiographic film is a feature of which of the following malignant tumours?

Squamous cell carcinoma
Osteosarcoma
Non-Hodgkin Lymphoma
Hodgkin Lymphoma

A

Osteosarcoma

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12
Q

Which is the most likely periosteal reaction in osteosarcoma patients?
Codman’s Triangle
Laminar
Sunray
Spiculated

A

Sunray

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13
Q

Which of the following statements is false for Burkitt’s lymphoma?

Burkitt’s lymphoma can be fatal without treatment
Burkitt’s lymphoma is associated with a malaria cofactor
Burkitt’s lymphoma is more commonly found in the mandible than the maxilla
Burkitt’s lymphoma responds well to chemotherapy

A

Burkitt’s lymphoma is more commonly found in the mandible than the maxilla

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14
Q

Patient presents with multifocal, ill-defined, non-corticated rediolucent lesion with infiltrative extensions on radiograph, with destruction of surrounding cortical boundaries and lamina dura. there is propensity for PDL space and loss of cortical crypts of developing teeth. What is the best differential diagnosis?

Lymphoma
multiple myeloma
Osteosarcoma
squamous cell carcinoma

A

Lymphoma

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15
Q

Which of the following is false of all malignant lesions in the oral cavity?
A) Are radiolucent due to osteolysis
B) Are non-corticated
C) Are irregular in shape
D) Cause cortical bone destruction

A

A) Are radiolucent due to osteolysis

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16
Q

Which of the following imaging modalities are not used for further investigations of malignant lesions?

Magnetic resonance imaging
Computerised tomography
Bone scan
Cone-beam computed tomography

A

Cone-beam computed tomography

17
Q

A 73 year old female patient was diagnosed with multiple myeloma. What are the possible radiographic features seen on her X-ray?

Scooped out appearance with the epicentre of the lesion at midroot.
Multiple, well-defined, non-corticated, circular, radiolucent leisions
Teeth appear to be floating.
A burst of sunrays like appearance at the area of destruction.

A

Multiple, well-defined, non-corticated, circular, radiolucent leisions

18
Q

What is true about malignant tumours?
Lymphoma arises most commonly at the PDL space, while leukaemia arises most commonly at the root apex
The chances of odontogenic cysts turning malignant are rare
Root resorption is a hallmark characteristic of malignant tumours arising at the jaw
CBCT is often used to investigate suspected malignant tumours

A

The chances of odontogenic cysts turning malignant are rare

19
Q

Which of the following is not a characteristic of squamous cell carcinoma?

Diagnosis cannot be done solely based off a clinical examination.
It is associated with HPV 16, 18, 31, 33 and 35.
It is most commonly seen on the soft palate.
Predisposing factors include iron-deficiency anaemia and syphillis.

A

It is most commonly seen on the soft palate.

20
Q

A 45 year old female patient who has prior history of radiotherapy comes into your clinic. She presents with painful ulcerative lesions in the posterior region. You take a periapical radiograph and notice extensive bone loss around the molars, resulting in a floating teeth apperance. Which of the following is not an appropriate differential diagnosis?

Periodontitis
Osteonecrosis of the jaw
Aggressive necrotising ulcerative gingivitis
Aggressive necrotising ulcerative periodontitis

A

Aggressive necrotising ulcerative gingivitis

21
Q

Which of the following is true?

All malignant tumours appear radiolucent.
Metastatic tumours are more common on the lateral border of the tongue and floor of the mouth.
Primary carcinomas are more common in the posterior mandible and maxilla.
Primary carcinomas may invade bone.

A

Primary carcinomas may invade bone.

22
Q

Which of the following is not a general radiographic feature of malignant tumours?

Non-corticated
Cortical bone destruction
Irregular shape
Usually radiopaque

A

Usually radiopaque

23
Q

A 61 year old male presents in your clinic complaining of a dull pain on the right side of his jaw for the past 3 months. On examination, you see an endophytic ulcerating lesion on the right side of his tongue. What would your most likely differential diagnosis be?

Angina bullosa haemorrhagica
Squamous cell carcinoma
Erythema multiforme
Fibroma

A

Squamous cell carcinoma

24
Q

Which of the following strains of HPV is not associated with squamous cell carcinoma?
16
18
31
64

A

64

25
Q

Which of the following radiographic features will we NOT expect to see in a Squamous Cell Carcinoma?

Ill-defined, non-corticated borders
Circular shaped
Widening of PDL space and loss of lamina dura
Destruction of cortical boundaries

A

Circular shaped

26
Q

Miss Teo presents to the clinic with an ulceration on the lower lip which has persisted for about 2 weeks already. Which of the following history would make us most suspcious of squamous cell carcinoma?
Sunlight
Alcoholism
Pipe Smoking
Poor Oral Hygiene

A

Pipe Smoking

27
Q

A lateral cephalometric radiograph was taken of a patient with multiple myeloma. Which description is least likely to be seen in the image?

Loss of lamina dura around teeth and loss of corticated crypts of follicles around unerupted teeth.
Multiple, well-defined, punched out oval lesions.
Raindrop on skull type of appearance.
Sunray appearance indicative of periosteal reaction.

A

Sunray appearance indicative of periosteal reaction.

28
Q

Which of the following is not a radiographic feature of squamous cell carcinoma?
Pathologic fractures
Periosteal reactions
Destruction of cortical boundaries
Ill-defined and non-corticated

A

Periosteal reactions

29
Q

Which is an incorrect match of radiographic description to the malignancy?

Squamous cell carcinoma: osteolytic, radiolucent bone
Multiple myeloma: punched out circular lesions
Leukemia: displacement of teeth in apical direction
Metastatic colorectal cancer: floating teeth

A

Leukemia: displacement of teeth in apical direction

30
Q

Which of the following best describes squamous cell carcinoma

Multiple, well-definied, non corticated, radiolucent, “punched out” circular lesions
Large, well-defined radiolucent lesion with corticated smooth-scalloped margins, apears to be expanding in an antero-posterior direction
ill-defined, non corticated, irregularly shaped mixed lesion, granular appearance with root resorption
ill-defined, non-corticated and irregularly shaped radiolucent lesion with floating teeth.

A

ill-defined, non-corticated and irregularly shaped radiolucent lesion with floating teeth.

OMOPOR (17 decks)

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