Clinical Investigation: Other tests Flashcards

1
Q

Which blood test is done to understand a patient’s kidney function?

A) ANA
B) Lipid panel
C) RPR
D) Serum BUN

A

D

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2
Q

Which test is most suitable for a patient on warfarin therapy prior to treatment?

A) aPTT
B) INR
C) PT
D) TT

A

B

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3
Q

Mr Tan, a sex worker, presented with reddish-purple raised lesions on his palate, a lesion characteristic of Kaposi sarcoma. Which of the following tests will be able to confirm that Mr Tan is HIV positive?

A) HIV culture
B) HIV lgM, lgG antibody
C) HIV p24 antigen test
D) Western blot

A

D

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4
Q

After a needle stick injury, the results for your Hepatitis B Panel shows: HBsAg positive, anti-HBc positive, IgM anti-HBc positive, anti-HBs negative. What is the interpretation?

A) I am acutely infected
B) I am susceptible to Hepatitis B
C) I am immune due to natural infection
D) I am immune due to Hepatitis vaccination

A

A

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5
Q

Whitish lesion with defined borders on lateral surface of tongue. How deep and where should tissue punch biopsy be done for this ulcer?

A) 1mm depth punched out in the middle of the white lesion
B) 3mm depth punched out at the margin between normal and abnormal area
C) 3mm depth punched out in the middle of the white lesion
D) 3mm depth punched out at the normal tissue next to the abnormal area

A

B

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6
Q

A patient presents with a dry mouth. The dentist decides to conduct a diagnostic test to assess the saliva flow rate. What could the diagnostic test be?

A) Biopsy of minor salivary glands
B) Sialometry
C) Sialochemistry
D) Radiographic imaging of the salivary glands

A

B

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7
Q

Which cell type is to be investigated in salivary gland biopsies for the diagnosis of Sjogren’s syndrome?

A) Basophil
B) Eosinophil
C) Lymphocyte
D) Neutrophil

A

C

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8
Q

Which of the following is NOT a blood disorder test?

A) Activated partial thromboplastin time (aPTT)
B) HbA1c test
C) Prothrombin time (PT)
D) Thrombin time (TT)

A

B

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9
Q

Which technique does not belong?

A) Aspiration
B) Amplification
C) Hybridization
D) Sequencing

A

A, culture technique, the rest are molecular techniques

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10
Q

A 35 year old male presents with white lesions on the lateral border of his tongue that cannot be rubbed off. Which is the LEAST appropriate diagnostic test?

A) Collection of tissue biopsy via surgical incision
B) In-situ hybridisation
C) PCR
D) Serology

A

D

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11
Q

When should you order laboratory based diagnostic tests?

A) Immediately after hearing the patient’s chief complaint
B) Only when the lesion presents with pus
C) Regardless of whether you have a differential diagnosis
D) When you want to rule out pathology such as malignancy

A

D

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12
Q

Ordering of laboratory tests are done so in a manner that is in line with certain basic principles. Which of the following is not sound basis for a clinician to order a laboratory tests?

A) To come to a differential diagnosis
B) To confirm diagnosis
C) Routine check prior to treatment or dispensing of medication
D) Rule out pathology such as infection or malignancy

A

A

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13
Q

Which of the following reasons is NOT justified when ordering a laboratory based investigation?

A) As a routine check prior to treatment
B) To confirm differential diagnosis
C) To rule out or confirm malignancy
D) When a differential diagnosis cannot be made clinically

A

D

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14
Q

Which of the following test is best used to confirm HIV diagnosis?

A) Antibody test
B) Antigen test
C) Western blot test
D) HIV1/HIV2 differential immunoassay

A

C

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15
Q

Which stain and pathogen correlates correctly?

A) Bacterial: KOH preparations
B) Fungal: Direct gram stain
C) Viral: Tzanck smear
D) Viral: KOH preparations

A

C

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16
Q

Which of the following tools can be used in the screening of oral cancers?

A) Sialometry
B) Sputum analysis
C) VELscope
D) Western blot

A

C

17
Q

Which procedure does not accurately correspond to the disease?

A) Excisional; chronic hyperplastic candidiasis
B) Exfoliative cytology; candidal hyphae
C) Immunofluorescence; pemphigus
D) Smears; acute pseudomembranous candidiasis

A

A

18
Q

Cytopathological investigations are microscopic examinations of free cells or tissue fragments. Which of the following collection methods are NOT used for cytopathological investigations?

A) Brush biopsy
B) Fine needle biopsy
C) Punch biopsy
D) Smear with swab

A

C

19
Q

What specific blood test should be performed for infectious diseases like Syphilis?

A) WBC count, CD4 count, HBsAg, HBsAb
B) FBC, Vitamin B12, Folate
C) PT, INR, aPTT, platelet count
D) Anti-ds-DNA, Anti-ss-DNA, Anti-Sm antibodies

A

A

20
Q

Which of the following techniques may not be useful for HIV diagnosis?

A) Immunoassay
B) Smear
C) Viral load
D) Western blot

A

B

21
Q

Which of the following investigations does NOT require injecting a radioactive dye?

A) Scintigraphy
B) Sialochemistry
C) Sialography
D) Sialometry

A

D

22
Q

Which of the following culture techniques is suitable for the collection of bacteria?

A) Smear/swab, blood, CSF fluid, tissue
B) Smear/swab, blood, CSF fluid, sputum
C) Smear/swab, blood, sputum
D) Smear/swab, aspirate, pus, blood, CSF fluid

A

D

23
Q

What is the interpretation of these results. HBsAg, anti-HBC, IgM anti-HBc positive, anti-Hbs negative

A) Immune due to natural infection
B) Immune due to Hepatitis B vaccination
C) Acutely infected
D) Chronically Infected

A

C

24
Q

Which of the following should not be a reason to order a laboratory based investigation?

A) Routine check prior to treatment
B) To check for malignancy
C) To make a differential diagnosis
D) To rule out infection

A

C

25
Q

Which of the following would be useful in the screening of HIV?

A) IgE, IgA, p24
B) IgE, IgM, p24
C) IgG, IgE, p24
D) IgG, IgM, p24

A

D

26
Q

Which of the following diseases is tested with the following blood test? RPR, VDRL, FTA-ABS

A) HIV
B) Syphilis
C) SLE
D) SJS

A

B

27
Q

A dentist suffered from a sharps injury and is tested for Hepatitis B. His results were HBsAg negative, anti-HBc negative and anti-HBs positive. What is the clinical interpretation?

A) Susceptible
B) Immune due to natural infection
C) Immune due to Hep B vaccination
D) Acutely infected

A

C

28
Q

Which of the following is true about clinical investigations?

A) Aerobic cultures are preferred for intra-oral infections
B) Patient infected with HSV1 has highest viral load on day 3 of infection
C) Serology is used to detect active infection
D) Superficial swabbing cannot be done for CMV

A

D

29
Q

Patient is suspected to have a malignancy in her breast. Which of the following laboratory based investigations is the most suitable for her?

A) Brush biopsy
B) Excisional biopsy
C) Fine needle biopsy
D) Incisional biopsy

A

C

30
Q

Which of the following is a suitable test to run for patients with suspected bleeding risk?

A) Bilirubin blood test
B) ESR
C) INR
D) Serum BUN

A

C

31
Q

Which of the following is incorrect about histopathological investigations?

A) Collection of tissue specimens can be through incision or excision.
B) It is used to diagnose and rule out pathology, especially malignancy.
C) PCR is an example of a histopathological investigation.
D) Tissue specimens must have all layers intact.

A

C

32
Q

Which of the following laboratory based investigations cannot be used for the diagnosis of HIV?

A) Culture technique
B) HIV-½ immunoassay
C) IgG, IgM antibody
D) Western blot

A

A

33
Q

Which of the following is not a test for anemias?

A) Ferritin test
B) Vitamin B12 test
C) CD4 count
D) Folate blood test

A

C

34
Q

Which of the following tests would not help to check if the patient has bleeding issues?

A) Prothrombin Time
B) Platelet count
C) International Normalized Ratio
D) White Blood Cell count

A

D

35
Q

Which of the following is wrong about types of biopsy?

A) Excisional biopsy: removes all off the lesion including the margin, only used for malignant tumour.
B) Exfoliative cytology: microscopic exam of cells scrapped from surface of oral lesion, smeared on glass slide and stain with toluidine blue; not good for diagnosing cancer.
C) Fine needle aspiration: used as adjunct, carried out for all cystic / fluctuant lesions.
D) Insitional biopsy: usually takes small piece of tissue (2.5-4mm) through punch

A

A

36
Q

A dentist was treating a Hep B positive patient when he got a needle stick injury. He was subsequently tested for Hep B and was found to be acutely infected. What are his results on the Hep B panel?

A) Negative for anti-HBs. Positive for HBsAg, anti-HBc, IgM anti-HBc.
B) Negative for IgM anti-HBc and anti-HBs. Positive for HBsAg and anti-HBc.
C) Negative for HBsAg and anti-HBc. Positive for anti-HBs.
D) Negative for HBsAg. Positive for anti-HBc and anti-HBs.

A

A