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Haematology and Immunology AM > White blood cells > Flashcards

White blood cells Flashcards

1
Q

What is the common origin of all blood cells?

A

Mulipotent haematopoietic stem cell aka haemocytoblast

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2
Q

What does the haemocytoblast differentiate to?

A

Common myeloid progenitor

Common lymphoid progenitor

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3
Q

What does the common myeloid progenitor differentiate to>

A

Megakaryocyte
Erythrocyte
Mast cell
Myeloblast

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4
Q

What does a myeloblast differentiate to?

A

Basophil
Neutrophil
Eosinophil
Monocyte

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5
Q

What does the common lymphoid progenitor differentiate to?

A

Natural killer cell

Small lymphocyte –> T and B lymphocyte

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6
Q

What are the types of phagocytic cells?

A

Neutrophils

Monocytes

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7
Q

What part of the immune system are neutrophils contained?

A

Innate

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8
Q

What is the function of neutrophils?

A

Ingest and destroy pathogens

Phagocytosis

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9
Q

What is the lifespan of neutrophils?

A

Short, ~1day

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10
Q

How are neutrophils regulated?

A

Immune responses

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11
Q

What are the types of monocytes?

A

MAcrophages

Dendritic cells

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12
Q

What is the function of the monocytes?

A

Ohagocytosis
Antigen presentation
Cytokine production

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13
Q

What are the types of lymphoid cells?

A

B lymphocytes
T lymohocytes
Natural killer cells

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14
Q

What are the types of T cell?

A

T helper cells

Cytotoxic T cells

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15
Q

What are the types of B cell?

A

Plasma cell

Memory cell

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16
Q

Where do lymphocytes get produced and mature?

A

Produced in bone marrow
T mature in thymus
B mature in bone marrow

17
Q

What are the functions of platelets?

A

Haemostasis

18
Q

Where is regulation of platelet production?

A

Liver

19
Q

What is the lifespan of platelets?

A

7 days

20
Q

What is and causes thrombocytopenia?

A

Low platelet count

Cause- decreased production, increased consumption, medication induced, other

21
Q

What causes neutrophilia?

A

Infection

Inflammation

22
Q

What causes neutropenia?

A

Decreased production- drugs, marrow failure
Increased consumption- sepsis, autoimmune
Altered function

23
Q

What causes lymphocytosis?

A

Infectious mononucleosis

Pertussus

24
Q

What causes lymphopenia?

A

Usually post viral

Haematology and Immunology AM (17 decks)

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