When the Immune System goes Wrong - Weeks 24&25 Flashcards
1
Q
Which antibodies are associated with Type I hypersensitivities?
A
IgE
2
Q
Which cells are implicated in the immune response to gluten in coeliac disease?
A
Th1 CD4+ T cells reacting to gliadin
3
Q
What type of a hypersensitivity is coeliac disease?
A
Type IV
4
Q
What are the 2 different classifications of autoimmune diseases?
A
Systemic
Organ-specific
5
Q
Which cells of the adaptive immune system respond to self antigens?
A
B and T cells
6
Q
What is chronic disease often associated with?
A
Broadening of the autoimmune response so that with time an expanding number of self-epitopes are recognised
7
Q
Does al autoimmunity result in disease?
A
No
