Welfare/ lab animals Flashcards
define the type of animal death: Spontaneous death
death of injury, illness, disease, old age, is an unassisted death
define the type of animal death: Death as an endpoint
Not intervening to kill the animal humanely before death naturally occurs, highly unethical, unlikely to be approved by the AEC
define the type of animal death: Humane endpoint
Euthanasia performed when welfare has deteriorated
define the type of animal death: Humane killing
Ending an animals life to facilitate use by humans (e.g. slaughter for meat, terminating unwanted animals)
define the type of animal death: Euthanasia
Killing an animal in a humane way when death is in the animal’s best interest (e.g. welfare)
define the type of animal death: Experimental endpoint
Time where an experiment has ended, animal may be: humanely killed, returned to flock, herd, sold, or released to wild (if appropriate)
define the type of animal model: induced (experimental) models
healthy animals which are induced with the condition to be studied (e.g. cancer)
define the type of animal model: spontaneous models
models where the disease naturally occurs (genetics/ mutant)
define the type of animal model: GEMMs
Genetically modified models: models that are deliberately genetically manipulated to study gene function
define the type of animal model: Negative model
control animals used to validate results
define the type of animal model: Orphan model
models where the disease has no human equivalent
define the type of animal model: homologous
animals that have the same causes, symptoms and treatment options (as human with the same disease)
define the type of animal model: isomorphic
animals share the same symptoms and treatment (not cause)
define the type of animal model: predictive
similar to human disease in some aspects but useful in making predictions about disease features
