Weight Loss Flashcards
A BMI of over what is classified as overweight?
25
A BMI of over what is obese?
30
A BMI of over what is morbid obesity?
35
Clinical trials have shown that orlistat produces a modest weight loss of approximately what?
5-10%
Orlistat is indicated for weight loss in adults (18 and over) who are overweight (body mass index of what value?) and should be taken in conjuction with a mildly hypocaloric, lower-fat diet.
greater than or equal to 28kg/m2
The recommended dose or orlistat is __mg capsule three times daily.
60mg tds
Orlistat should be taken when?
Immediately before, during or up to 1 hour after each main meal. If the meal contains no fat = no orlistat.
The patient should stop taking orlistat if weight loss has not been achieved after how long?
12 weeks.
What are the main side effects of orlistat?
GI:
Faecal urgency + incontinence
Oily evacuation and spotting
Flatus and abdominal pain
How can orlistat side effects be minimised?
Restricting fat to less than 20g per meal.
Why is supplementation of diet with fat-soluble vitamins (A, D, E and K) recommended? How is it achieved?
Reduced absorption of fat-soluble vitamins from food sources because of reduced fat absorption on the whole.
Just take a multivitamin.
Why cant orlistat and warfarin be used together?
Vitamin K is fat soluble (ADE as well) so absorption is reduced with orlistat.
Decreased vitamin K =increased effect of warfarin = bleeding.
Can Orlistat be used in pregnancy of breastfeeding?
no evidence so no
