Vaginal Discharge

Question 1

Drug interactions of note with fluconazole oral?

Answer 1

1. Anticoagulants (warfarin etc)
2. Ciclosporin (organ rejection, kidney etc)
3. Rifampicin (TB)
4. Phenytoin (Epilepsy)
5. Tacrolimus (organ rejection)

Question 2

Rationale for OTC license of over 16 but under 60 for thrush medicines

Answer 2

Thrush is less common outside of these age groups and other indications more likely, refer.

Question 3

Thrush: Rationale for OTC license restriction of: Has had two episodes in 6 months, and has not consulted her GP about the condition for more than one year.

Answer 3

Good practice as repeat infection is more likely to indicate misdiagnosis or predisposing risk factors.