Week 9: Non-heath application Flashcards
applications of non medical natural compounds
cosmestics, argiculture, food and beverage, manufacturing.
Cosmetics history
Romans: used swan fat or donkey milk to soften wrinkles
Phenylenediamine (coal tar) for eye mascara. caused blindness
Ancient egyptians used henna plant for hair ad skin dye
people would bleed themselves with leeches to be pale
women whitened face with ‘ceruse’ made from vinegar and lead causes death
Cosmetics natural compounds
Plant oils: coconut,sunflower, olvies
herbal agents: tumeric (cucumin). sage. thyme, garlic, green/black tea (catechins), aloe vera (mannose-6-phosphate, lupeol), oats, basil, onion (flavonoids), grape seed extracts (procyanidins).
Cosmetics Curcumin
have potential in cosmeceuticals as antioxidant. antiinflam, and skin lightening agents.
In vitr curcuminoids inhib collagenase.elastase and hyaluronidase. used to treat eczema.
Catechins Cosmetics
catechins (flavan-3-ols0
can have up to 4 isomers. commonly found in cacao, green/black tea
used as anti-aging properties.
Agriculture/ what are the three main types
plant derived pesticides - ‘botanicals’
pyrethroids
rotenoids
nicotinoids
Pyrethroids
pyrethrins are natural compounds that can be etracted from chrysanthemum flowers.
Pyrethroids are similar to pyrethrins but ar eman made and used to control insects.
examples of pyrethroids and mode of action
type 1: Allethrins
Type 2: Cypermethrins
affects ion channels and cause imbalance i ion movement and cause axon-neuron function breakdown
Rotenoids
Rotenone: C23H22O6
build up of electrons, resulting in oxygen reduction to reactive oxygen species (ROS) this leads to cell stress-cell death.
Neonicotenoid
act on neurotransmitters similar to nicotine.
Imidacloprid; acts on the incest central nervous sytem by interfering with stimli, blocking the nicotinergic neuronal pathway. causes accummulation of acetylcholine resulting in paralysis and death.
Food and beverage
Polyphenols
nutraceuticals
orgnaic F&B
Food and Beverage applications
Polyphenols
Flavonols
Anthocyanins
Sources: Grape seed
Green tea
Apple
Applications: Functional foods
Functional beverages
Dietary supplements