Week 9- Endocrine Flashcards

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1
Q

what r hormones

A

Hormones are chemicals released by glands, in small amounts, that travel in
the bloodstream.

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2
Q

how do hormones work

A

The hormones bind to specific receptors on cells in target organs.

This triggers a response in the target cell, resulting in a change of activity.

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3
Q

examples of some hormones

A

insulin
Glucagon
Adrenalin
ADH (anti diuretic hormone)
Thyroxine
Oxytocin
Testosterone
Oestrogen
Progesterone
LH
FSH

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4
Q

what is homeostasis

A

maintain an equilibrium within the
body to allow optimum functioning of
physiological systems

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5
Q

3 types of hormones and their half lives

A

Amines: approx 1 day
Peptides: minutes-hour
Steroid: hours

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6
Q

some endocrine system glands

A

Skin
Kidney
Liver
Intestines
Heart

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7
Q

what is the master gland

A

Pituitary Gland:
Small bean sized structure, found at
the base of the brain and has 2 parts
an anterior & posterior
*It is found close to the hypothalamus

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8
Q

adh full form

A

anti diuretic hormone

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9
Q

why is adh released

A

released when the body is dehydrated where the volume of
water in blood plasma has dropped.

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10
Q

how does adh work

A

hypothalamus triggers the release
of ADH from the posterior pituitary
into the blood stream

target organ is the kidney

Urine output is reduced as water is
retained in the blood

helps to return water levels back
towards normal. This is an example of negative feedback

the walls of the nephrons reabsorb
water from the forming urine and return it back to the
bloodstream

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11
Q

where is thyroid gland found

A

neck

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12
Q

how does thyroid regulation work

A

If levels of thyroid hormone drop,
hypothalamus releases TRH, which in turn triggers the anterior pituitary to secrete TSH into the blood.

thyroid gland responds by secreting
thyroid hormones T3 & T4 into the blood

Increased metabolic rate and increased levels of thyroid hormone in the blood, triggers the cessation of flow of TRH from the hypothalamus and TSH from the pituitary
gland

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13
Q

when is oxytocin released

A

*Released during labour to increase
uterine contractions

*helps lactates when baby begins to suckle via let down reflex

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14
Q

FSH full form and function

A

*Follicle stimulating hormone
*Released early in the menstrual cycle days 1-10
*Triggers the maturation of a follicle into an ovum in the ovary

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15
Q

LH full form and function

A

*Luteinising hormone
*sharp rise in LH around days 12-14
*causes the ovum to be released from the ovary (ovulation)

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16
Q

what is insulin

A

A peptide hormone secreted by
the pancreas, in response to
increased glucose in the blood

17
Q

how does insulin work

A

Binds to receptors on cell
membranes in liver and muscle cells

18
Q

how is glucose stored

A

*The cells of the liver and muscle
cells respond by taking in more
glucose and converting it to
glycogen for storage
*More conversion of glucose into
fat in adipose cells

19
Q

wht type of disease is diabetes

A

diabetes is a chronic disease

20
Q

types of diabetes

A

type I and type II (mellitus diabetes)

21
Q

common symptoms of diabetes

A
  • Increased thirst and hunger
  • Need to urinate excessively
  • Tiredness
  • Weight loss
  • Presence of glucose in the urine, which can
    lead to frequent UTIs & genital itching &
    regular episodes of thrush.
  • Blurred vision
  • Changes in sensation due to nerve damage.
22
Q

how does type 1 diabetes affect body

A

*Pancreas is unable to produce
insulin
*It may result as an autoimmune
response, the body’s immune
system attacks its own cells

23
Q

controls for type 1 diabetes

A
  • Controlled by injections or
    infusions of insulin 2 or four times
    a day.
    *cannot be taken by mouth because it is a polypeptide so would be digested.
  • Blood sugar levels need to be
    checked regularly.
  • dose of insulin must be
    matched exactly to the glucose
    intake.
  • Unconsciousness result if too
    much insulin is taken; the blood
    glucose level can drop too low.
24
Q

how does type 2 diabetes affect body

A

*Insulin receptors on the cell membrane lose their responsiveness to insulin. Also could be due to an inadequate supply
of insulin

25
Q

control for type 2 diabetes

A
  • Controlled by lifestyle choices.
  • Diet and exercise are critical in
    regulating the intake of carbohydrate.
  • Matching intake to the amount of
    exercise taken.
  • Also need to take insulin or take drugs that stimulate insulin production.
  • Other drugs can slow down the rate at which the body absorbs glucose from the intestine, preventing the high spikes in blood sugar.
26
Q

what is hypothydroidism

A

*Lack of T3 & T4 will result in a slowed metabolism

27
Q

how to treat hypothyroidism

A

Can be treated with daily hormone
tablets, that will need to taken for the rest of the patients life

28
Q

symptoms of hypothyroidism

A

onstant tiredness, weight gain & depression, muscle aches, a sensitivity to the cold, dry skin & hair

29
Q

what is hyperthyroidism

A

Too much of the thyroid hormones are released

30
Q

symptoms of hyperthyroidism

A

Raises metabolic rate which can lead to weight loss, changes in heart rhythms, increased sweating and problems sleeping, among others

31
Q

how to treat hyperthyroidism

A

An overactive thyroid is treatable with medication or a form of radiotherapy which kills some of the overactive thyroid cells or surgery to remove part of the thyroid