Week 9 Antibiotics part 2 Flashcards
Azithromycin
Zithromax
Z-PAK
Tri-Pak; Z-Pak; tablets; packet; suspension, reconstituted
Antibiotic
Macrolide
Pulmonary inf (asthma/COPD, pneumonia); otitis media; chlamydia
N/V/D/abdominal pain; Qtc prolongation; elevated liver enzymes; flatulence
Warfarin; Simva/Atorva/Lovastatin; Digoxin
Altered cardiac conduction/cardiac risk
PATIENT COUNSELINGS
- can take with or without food
- take zmax on empty stomach
- avoid aluminum or magnisium- antacids expect zmax
Ciprofloxacin
Cipro/Cipro XR
Eye: Ciloxan; ear: Cetraxal
tablets; suspension, reconstituted; eye drops; eye ointment; ear drops
Antimicrobial
Antibiotic
Fluoroquinolone
Not FDA approved < 18 years; UTI; Resp infections
N/V/D/abdominal pain; skin rash/photosensitivity; tendonitis/tendon rupture; Qtc prolongation
Antacids/calcium/iron; Corticosteroids; NSAIDs; Antidiabetic agents; Warfarin; Antiarrhythmics
Photosensitivity; Altered cardiac conduction; BBW tendon rupture and myasthenia gravis
PATIENT COUNSELINGS
- apply sunscreen before going outside
- drink alot of water
- report any symptoms of muscle weakness
- can take with or without food
- suspension can be store in the room temp and shake well before use
Clarithromycin
Biaxin
IR and ER tablets; suspension, reconstituted
Antimicrobial
Antibiotic
Macrolide
Pulmonary inf (asthma/COPD, pneumonia); otitis media
N/V/D/abdominal pain; Qtc prolongation; elevated liver enzymes; altered taste
Warfarin; Simva/Atorva/Lovastatin; Digoxin
Altered cardiac conduction/cardiac risk; ER tablets avoided in most GI disorders; lactose in some preparations
PATIENT COUNSELINGS
- can take with or without food
- take zmax on empty stomach
- avoid aluminum or magnisium- antacids expect zmax
Clindamycin
Cleocin
tablet; ER tablet; suspension
Antimicrobial
Antibiotic
Lincosamide
SSTI/MRSA; Aspiration pneumonia; Alternative to penicillin for strep throat or dental prophylaxis
N/V/D/abdominal pain; esophagitis; rash; c diff
Cyclosporine; erythromycin; neuromuscular blocking agents
BBW: c diff/pseudomembranous colitis; superinfection; liver dysfunction
PATIENT COUNSELINGS
- discontinue if experiencing significant diarrhea
- do not treat diahhrea with imodium (loperamide)
- take with full glass of water
- stay upright at least 30mins after the doses
Moxifloxacin
Avelox
eye: Vigamox, Moxeza
oral tablet; eye drops
Antimicrobial
Antibiotic
Fluoroquinolone
Not FDA approved < 18 years; Resp infections
N/V/D/abdominal pain; skin rash/photosensitivity; tendonitis/tendon rupture; Qtc prolongation
Antacids/calcium/iron; Corticosteroids; NSAIDs; Antidiabetic agents; Warfarin; Antiarrhythmics
Photosensitivity; Altered cardiac conduction; BBW tendon rupture and myasthenia gravis
PATIENT COUNSELINGS
- apply sunscreen before going outside
- drink alot of water
- report any symptoms of muscle weakness
- can take with or without food
Trimethoprim / Sulfamethoxazole (TMP/SMX)
Bactrim/Bactrim DS
Septra
SS tablet; DS tablet; suspension
Antimicrobial
Antibiotic
Sulfonamide
UTI; Resp infections; SSTIs
N/V/D; Skin Rash; Hyperkalemia; Myalgia; Anorexia; Photosensitivity; Rare but serious: liver and kidney failure, blood dyscrasias
Methotrexate; Warfarin; Oral hypoglycemic agents; ACE-Is, ARBs, potassium sparing diuretics, K+ supplements (hyperkalemia)
Pregnancy Category D (kernicterus, late stage); G6PD deficiency; Folate deficiency; Sulfa allergy
PATIENT COUNSELINGS
- apply sunscreen before going outside
- drink full water
- can take with food to minimize GI
- use should be avoided in pregnancy and breastfeeding
Levofloxacin
Levaquin
Tablet, solution, eye drops
Antimicrobial
Antibiotic
Fluoroquinolone
Not FDA approved < 18 years; UTI; Resp infections
N/V/D/abdominal pain; skin rash/photosensitivity; tendonitis/tendon rupture; Qtc prolongation
Antacids/calcium/iron; Corticosteroids; NSAIDs; Antidiabetic agents; Warfarin; Antiarrhythmics
Photosensitivity; Altered cardiac conduction; BBW tendon rupture and myasthenia gravis
PATIENT COUNSELINGS
- apply sunscreen before going outside
- drink alot of water
- report any symptoms of muscle weakness
- can take with or without food
Erythromycin
E.E.S. 400, Ery Tab
Macrolide
Indication: used for pro-motility (causes significant GI irritation/bowel movements) or in “Magic Mouthwash”; limited use as antibiotic
PATIENT COUNSELINGS
- can take with or without food
- take zmax on empty stomach
- avoid aluminum or magnisium- antacids expect zmax
which macrilide antibiotic tablet may need to be avoided in patietns with lactose intolerance?
a. azithromycin
b. clarithromycin
c. clindamycin
d. erythromycin
b. clarithromycin
which of the follwoing macrolide antibiotics is typically used to stimulate gastroparesis?
a. azithromycin
b. clarithromycin
c. clindamycin
d. erythromycin
d. erythromycin
avelox is indicated for treatment of community acquired pneumonia
true
false
true
Your patient has a documented allergy for Bactrim resulting in rash. Which of the following would have the greatest rish of cross reactivity?
a. penicillin
b. sulfasalazine
c. furosemide
d. glyburide
b. sulfasalazine
Clindamycin is a macrolide anitibitoic
true
false
false
