Week 13 Immunologic medications Flashcards
Methylprednisolone
Medrol
Oral Corticosteroid
***available as 21 tab dose pack
Hormonal
Systemic Corticosteroid
Decrease production of chemical mediators of inflammation
Allergic conditions (exacerbation), respiratory infection, rheumatologic conditions
Short-term: elevated blood glucose, elevate blood pressure, hunger; long-term: emotional, skin abnormalities, osteoporosis, weight gain, weakened immune system
Warfarin, fluoroquinolones
Caution in DM and OP; risk of adrenal suppression w/long-term, CI: live vaccines
PATIENT COUNSELINGS
- take first think in the morning if possible
- take with food or milk
Prednisone
Deltasone, Prednisone Intensol (liquid solution)
Oral Corticosteroid
***available as 21 tab dose pack
Hormonal
Systemic Corticosteroid
Decrease production of chemical mediators of inflammation
Allergic conditions (exacerbation), respiratory infection, rheumatologic conditions
Short-term: elevated blood glucose, elevate blood pressure, hunger; long-term: emotional, skin abnormalities, osteoporosis, weight gain, weakened immune system
Warfarin, fluoroquinolones
Caution in DM and OP; risk of adrenal suppression w/long-term, CI: live vaccines
PATIENT COUNSELINGS
- take first think in the morning if possible
- take with food or milk
Triamcinolone
Triderm (cream)
Trianex (ointment)
Topical
Hormonal
Topical Corticosteroid
Decrease inflammation, provide itching relief, vasoconstrict
Skin conditions (i.e. poison ivy, psoriasis)
dry skin, skin breakdown, avoid occlussive dressings to prevent systemic absorption
PATIENT COUNSELINGS
- apply a thin layer to the affected area
- wash hands before and after application
Hydrocortisone
Cortaid (otc)
Locoid (Rx)
Topical
Hormonal
Topical Corticosteroid
Decrease inflammation, provide itching relief, vasoconstrict
Skin conditions (i.e. poison ivy, psoriasis)
dry skin, skin breakdown, avoid occlussive dressings to prevent systemic absorption
Allopurinol
Zyloprim
Aloprim
PO, IM
Antiinflammatory
Gout Therapy
Xanthine Oxidase Inhibitior
Gout, Cancer
therapy0induced hyperuricemia, calcium oxalate stones
Urticaria; skin rash; LFT elevation; diarrhea/nausea
Azathioprine, ACE-I, Thiazide diuretics
AHS (HLA-b*5801); Precipitation of acute gouty attack
PATIENT COUNSELINGS
- immeidately report any type of skin rash to your health care provider
- maintain adequate hydration
- take with food to minimize Gi upset
- avoid vitamin C
Methotrexate
Trexall
Rheumatrex
PO, IM
Immunosuppressant
Anti-inflammatory
DMARD
Chemotherapy agent; Psoriasis; Rheumatoid arthritis; Various immunologic conditions
Alopecia; Thrombocytopenia; Leukopenia; Liver Dysfunction; GI (N/V/D, stomatitis)
NSAIDs, ASA, FA
Boxed Warning: Bone Marrow Suppression, Gastic Toxicity, Hepatotoxicity, Opportunisitic Infections; CI: alcoholism, alcoholic liver disease
PATIENT COUNSELINGS
- review apporpriate dose and schedule with patient
- no live vaccine
- watch for flank pain, sore mouth and throat, bleeding/bruising. fever and malaise
Do you think topical therapy would cause these
side effects (i.e. elevated blood glucose?)
A. Yes
B. No
B. No
What would be an accurate counseling point for a 5-day course of prednisone? A. You might experience some irritation/breakdown of skin B. You should take this medication at bedtime C. You will be at greater risk for osteoporosis D. You may experience increased appetite
D. You may experience
increased appetite
Patients taking allopurinol cannot take
azathioprine under any circumstance
A. True
B. False
B. False
What side effect would you expect in a patient taking Trexall®? A. GI bleed B. Constipation C. Kidney dysfunction D. Opportunistic infection
D. Opportunistic infection
Which medication has a boxed warning for hepatotoxicity? A. Zyloprim® B. Trexall® C. Delasone® D. Locoid®
B. Trexall®
Which medication can cause a severe skin rash? A. Aloprim® B. Medrol® C. Cortaid® D. Rheumatrex®
A. Aloprim®
