Week 10 Antibiotics part 3

Question 1

Acyclovir

Answer 1

Zovirax

topical; tablet; capsule; suspension

Antimicrobial

Antiviral

Viral DNA polymerase inhibitor

HSV; VZV

Malaise; N/V/D; HA; crystalluria/kidney dysfunction

Probenecid; varicella/zoster(live) vaccines

CNS effects; kidney impairment; use within specified time frames

PATIENT COUNSELINGS

• initiate medication use ASAP
• take with full glass of water to prevent kidney
• avoid live vaccine

Question 2

Fluconazole

Answer 2

Diflucan

Tablet; suspension, reconstituted

Antimicrobial

Antifungal

Triazole antifungal

Candidiasis (mouth and vaginal infections)

N/V/D/abdominal pain; Rash; elevated LFTs

Atorva/simva/lovastatin; sulfonylureas

Arrhythmias

PATIENT COUNSELINGS

• can take with or without food
• if taking weekly, take on the same day at the same time every week

Question 3

Metronidazole

Answer 3

Flagyl
Metrogel

IR tablet, ER tablet, capsule; suspension, reconstituted; topical gel

Antimicrobial

Antibiotic/Antiprotozoal

Nitroimidazole

Anaerobic infections; C diff; Bacterial vaginosis; Trichomoniasis

HA; N/D; Abnormal taste (metallic)

Alcohol; warfarin

Disulfiram-like reaction; superinfection with prolonged use

PATIENT COUNSELINGS

• complete FULL course of therapy, even if start to feel better
• avoid consuming alcohol while taking this medication AND for three days after finishing therapy
• ER should be taken on empty stomach
• IR can be administrated with food to minimize stomach upset
• patients taking warfarin should be informed to contact their warfarin prescriber to inform them of the drug therapy

Question 4

Oseltamivir

Answer 4

Tamiflu

capsule; suspension, reconstituted

Antimicrobial

Antiviral

Neuraminidase inhibitor

Influenza A/B

HA; N/V/D; Neuropsychiatric events (children); Stevens Johnson

Live, attenuated influenza vaccine

Immunocompromised

** MUST BE STARTED WITH 48 HOURS OF SYMPTOMS*

PATIENT COUNSELINGS
- full course

Question 5

Valacyclovir

Answer 5

Valtrex

tablet

Antimicrobial

Antiviral

Viral DNA polymerase inhibitor

HSV; VZV

Malaise; N/V/D; HA; crystalluria/kidney dysfunction

Probenecid; varicella/zoster(live) vaccines

CNS effects; kidney impairment; use within specified time frames

Question 6

Mupirocin

Answer 6

Bactroban

ointment; nasal ointment; cream

Antimicrobial

Topical Antibiotic

impetigo; nasal MRSA; secondary skin infections

Burning; Stinging; Pruritus; Pain; Erythema; Secondary wound infections

N/A topical

Superinfection; avoid eye contact

Question 7

Which agent is used in the treatment of
C. difficile?
A. Fluconazole
B. Metronidazole
C. Oseltamivir
D. Valacyclovir

Answer 7

B. Metronidazole

Question 8

Which agent is indicated for treatment of
vaginal candidiasis?
A. Fluconazole
B. Metronidazole
C. Oseltamivir
D. Valacyclovir

Answer 8

A. Fluconazole

Question 9

For oseltamivir to be clinically beneficial, it must be
started within how many hours of symptom onset ?
A. 12
B. 24
C. 48
D. 72

Answer 9

C. 48

Question 10

Which agent can be utilized in the
treatment of herpes simplex?
A. Acyclovir
B. Valtrex
C. Valacyclovir
D. Zovirax
E. All choices are correct

Answer 10

E. All choices are correct

Question 11

Which agent if combined with alcohol
can cause a disulfiram reaction?
A. Fluconazole
B. Latanoprost
C. Metronidazole
D. Oseltamivir
E. Valacyclovir

Answer 11

C. Metronidazole

Question 12

Which of the following antibiotics would NOT
require increased INR monitoring following a
course of therapy?
A. Doxycycline
B. Penicillin
C. Amoxicillin/Clavulanate
D. Cefdinir
E. Mupirocin

Answer 12

E. Mupirocin