Week 14 Women's health Flashcards
Conjugated Estrogens
Premarin
Hormonal
Female Sex Hormones
Estrogen Supplementation
Menopause (vasomotor symptoms, vaginal atrophy); primary ovarian failure
Weight gain, Headache, menstruation, breast pain, blood clots
Levothyroxine
Boxed Warning: risk of endometrial and breast cancer, do not use to prevent CV disease/dementia, lowest dose for shortest time; precauction: smokers
PATIENT COUNSELINGS
- take at bedtime to minimize side effects
- discuss long term risks with patients
- sould attempt to taper every 3-6months
Ethinyl estradiol/Drospirenone
Giavani
Yasmin
Yaz
Hormonal
Contraceptive
Estrogen/Progestin Contraceptive
Contraception; acne; premenstrual dysmorphic disorder
breakthrough bleeding, nausea, breat enderness, changes in menstrual flow, bloating/edema/weight gain
Antibiotics, Anticonvulsants
Boxed Warning: risk of breast cancer, CV risk, cigarette smoking, shortest duration at lowest dose; Pre: women>35, estrogen cancers, may adversely affect lipid levels; CI: history of clots, breastfeeding, pregnancy
Clinical Pearls
- good option for patient with severe acne
- affects mood stability significantly
Ethinyl estradiol/Norethindrone
Loestrin
Junel
Microgestin
Hormonal
Contraceptive
Estrogen/Progestin Contraceptive
Contraception; acne
breakthrough bleeding, nausea, breat enderness, changes in menstrual flow, bloating/edema/weight gain
Antibiotics, Anticonvulsants
Boxed Warning: risk of breast cancer, CV risk, cigarette smoking, shortest duration at lowest dose; Pre: women>35, estrogen cancers, may adversely affect lipid levels; CI: history of clots, breastfeeding, pregnancy
Clinical Pearls
- decrease estrogen dose
- prevent ovulation
Ethinyl estradiol/Norgestrel
Ogestrel
Hormonal
Contraceptive
Estrogen/Progestin Contraceptive
Contraception
breakthrough bleeding, nausea, breat enderness, changes in menstrual flow, bloating/edema/weight gain
Antibiotics, Anticonvulsants
Boxed Warning: risk of breast cancer, CV risk, cigarette smoking, shortest duration at lowest dose; Pre: women>35, estrogen cancers, may adversely affect lipid levels; CI: history of clots, breastfeeding, pregnancy
Etonogestrel/Ethinyl Estradiol
Nuvaring
Topical/Local
Hormonal
Contraceptive
Estrogen/Progestin Contraceptive
Contraception
Antibiotics, Anticonvulsants
Boxed Warning: risk of breast cancer, CV risk, cigarette smoking, shortest duration at lowest dose; Pre: women>35, estrogen cancers, may adversely affect lipid levels; CI: history of clots, breastfeeding, pregnancy
PATIENT COUNSELINGS
- insert the ring once every 3 consective weeks
- pay remove for up to 4th week
- remove for one week to stimulate menses
- press sides of the ring together between fingers
- insert folded into the vagina
- does not require specific placement
- do not reuse
- do not flush
oxybutynin
Oxytrol (patch), Gelnique (gel)
Ditropan, Ditropan XL
PO, Topical, Patch
Urinary
Overactive Bladder
decrease urine leakage by preventing of urinary tract muscles
Anticholinergic that decreases activity of the detrusor muscle in the bladder
Overactive bladder
Dry mouth, sedation/confusion/memory impairment, blurred vision, urinary retention, constipation
Anticholinergics (diphenhydramine, muscarinic antagonist inhalers), medicatons that prolong the Qtc
Precaution: Prostate issues, parkinsons, dementia; CI: urinary retention, decreases GI motility, narrow angle glaucoma
PATIENT COUNSELINGS
- caregivers of elderly patients should be instructed to water for changes in cognitive function
- discuss signs and symptoms of anthicholiergic side effects such as decrease urination, sweating and constipation
Solifenacin
Vesicare
Urinary
Overactive Bladder
decrease urine leakage by preventing of urinary tract muscles
Anticholinergic that decreases activity of the detrusor muscle in the bladder
Dry mouth, sedation/confusion/memory impairment, blurred vision, urinary retention, constipation
Anticholinergics (diphenhydramine, muscarinic antagonist inhalers), medicatons that prolong the Qtc
Precaution: Prostate issues, parkinsons, dementia; CI: urinary retention, decreases GI motility, narrow angle glaucoma
PATIENT COUNSELINGS
- caregivers of elderly patients should be instructed to water for changes in cognitive function
- discuss signs and symptoms of anthicholiergic side effects such as decrease urination, sweating and constipation
Tolterodine
Detrol
Detrol LA
Urinary
Overactive Bladder
decrease urine leakage by preventing of urinary tract muscles
Anticholinergic that decreases activity of the detrusor muscle in the bladder
Overactive bladder
Dry mouth, sedation/confusion/memory impairment, blurred vision, urinary retention, constipation
Anticholinergics (diphenhydramine, muscarinic antagonist inhalers), medicatons that prolong the Qtc
Precaution: Prostate issues, parkinsons, dementia; CI: urinary retention, decreases GI motility, narrow angle glaucoma
PATIENT COUNSELINGS
- caregivers of elderly patients should be instructed to water for changes in cognitive function
- discuss signs and symptoms of anthicholiergic side effects such as decrease urination, sweating and constipation
Clinical Pearls
- side effects are less likely with long acting products
Which hormone in hormone replacement medications do you think is responsible for side effects of these medications? A. Estrogen B. Progesterone C. Testosterone
A. Estrogen
Which birth control is not available in an oral (tablet) dosage form? A. ethinyl estradiol/norgestrel B. ethinyl estradiol/etonogestrel C. ethinyl estradiol/drospirenone D. ethinyl estradiol/norethindrone
B. ethinyl estradiol/etonogestrel
Do you think that antibiotics affect the effectiveness of birth control? A. Yes B. No C. Data is pretty mixed
C. Data is pretty mixed—I personally caution on the safe side that it’s mixed so 2 forms of contraception are best while taking abx
Which patient would be least at risk for blood clots from hormonal contraceptives? A. 37 year old healthy female B. 21 year old smoker female C. 26 year old female with history of blood clots D. 29 year old female with asthma
D. 29 year old female with asthma
Which hormonal contraceptive is indicated for use in PMD? A. Ogestrel® B. Nuvaring® C. Loestrin® D. Yaz®
D. Yaz®
Which hormone significantly declines in menopause? A. Testosterone B. Progesterone C. Estrogen
C. Estrogen
Which incontinence medication is available as a patch? A. oxybutynin B. solifenacin C. tolteridone
A. oxybutynin