Week 8 - Understanding life with ADHD Flashcards

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1
Q

What is meant by a neurodevelopmental condition?

A

A condition stemming from atypical early development of the nervous system due to the interaction of genetic, neurobiological and environmental influences

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2
Q

In children and adolescents, are the majority of people diagnosed with ADHD male or female?

A

Male

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3
Q

What are people diagnosed with ADHD more at risk of developing in later life?

A

Learning, behavioural and emotional problems

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4
Q

What condition is commonly comorbid with ADHD?

A

Autism

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5
Q

What are some of the common features of the conditions comorbid with ADHD?

A
  • Dyslexia
  • Conduct disorder
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6
Q

Is it possible to diagnose ADHD if symptoms were only present as an adult?

A

No

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7
Q

What are the three subtypes of ADHD?

A
  • Inattentive
  • Hyperactive/impulsive
  • Combined
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8
Q

What is hyperkinetic disorder?

A

A condition which closely aligns with ADHD and includes symptoms of inattention and overactivity

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9
Q

Are there differences in diagnosis in terms of presentation types of ADHD? What are they?

A

Yes - females are more likely than males to have inattentive presentation

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10
Q

How much greater is the risk of being diagnosed with ADHD for children who have siblings/other family members with a diagnosis?

A

Nine times

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11
Q

What is meant by concordance?

A

The probability that a pair of individuals will both have a condition, given that one of them has it

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12
Q

What is meant by heritability?

A

The degree to which variability of a condition in the population can be accounted for by genetics

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13
Q

What is the mean (average) heritability rate for ADHD across the world?

A

74%, making ADHD one of the most heritable psychiatric conditions

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14
Q

To date, what are the two main methods of studies used to identify specific genes that may play a role in ADHD?

A
  • Linkage studies
  • Candidate gene studies
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15
Q

What are candidate gene studies?

A

Studies in which researchers select genes based on neurobiological studies or theoretical considerations and compare these directly in different groups of people

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16
Q

What is meant by a SNP?

A

A SNP is a change to a single nucleotide in a sequence of DNA

17
Q

What is meant by the term absolute risk?

A

The probability of a condition or disease developing over a particular period of time

18
Q

What is meant by the term relative risk?

A

A measure of risk calculated by comparing the absolute risk of people exposed to a risk factor with those who have not

19
Q

What are some of the prenatal factors which can increase the risk of ADHD?

A
  • Premature birth
  • Low birth weight
  • Maternal smoking in pregnancy
  • Maternal andidepressant use in pregnancy
  • Maternal stress in pregnancy
20
Q

What is the highest prenatal risk factor for ADHD?

A

Premature birth

21
Q

ADHD affects roughly how many people?

A
  • 6 in 100 children/adolescents
  • 3 in 100 adults
22
Q

What are the 3 core symptoms of ADHD?

A
  • Inattention
  • Impulsivity
  • Hyperactivity
23
Q

The neurobiology of ADHD is thought to revolve around which two structures of the brain?

A
  • Superior calliculus
  • Prefrontal cortex