Week 8: Ophthalmic Flashcards
What are the common eye complaints?
- Dry eye
- Allergy eye
- Corneal edema
- Age related macular degenration
- Contact lens related problems
What are the exclusion of eye companies?
- Eye pain
- Blurred vision not associated with use of ophthalmic ointments
- Sensitivity to light
- Blunt trauma to eye
- History of contact lens wear
- Chemical exposure to eye
- Eye exposure to heat, excluding sun exposure
- Symptoms that have persisted for >72 hours
- Signs and symptoms of infection of the eyelids (e.g., red, thickened eyelids; scaling)
- Blunt trauma to eye
- Exposure of the eye to chemicals
- Head lice
- Macular degeneration
- Hordeolum, chalazion, blepharitis
What is dry eye?
May be the result of anything that disrupts healthy tear film
What are the symptoms of dry eye?
- Blurred vision
- Stinging
- Burning
- Sensitivity to light
- Difficulty wearing contact lenses
- Eye fatigue
What is dry eyes associated with?
- the aging process
- lid or corneal defects
- Sjögren syndrome
- Bell’s palsy
- thyroid disorder–related eye disease
- collagen diseases (e.g., rheumatoid arthritis)
- Medications
What are types of medication for dry eye?
- Anticholinergic drugs (e.g., antihistamines)
- Decongestants
- Diuretics
- Beta Blockers
What are the risk factors of dry eyes?
- AGE – increased risk among elderly
- SEX – increased risk among women
- DIET – especially diets low in fatty acids
- HISTORY OF SURGERY OR CONTACT USEOF CONTACT LENSES
How do you prevent dry eyes?
- Add moisture to the air especially during dry seasons
- Stop smoking and avoid smoke
- Avoid air blowing directly on the eyes (moisture chamber goggles)
- Add omega-3 rich foods to diet (in consultation with prescriber)*
- Take breaks during long tasks that require visual concentration
What are the treatment goals of dry eyes?
- Alleviate the dryness of the ocular surface
- Relieve the symptoms of irritation
- Prevent possible corneal and non corneal tissue damage
What are the non pharms for dry eyes?
- Avoid environments that increase evaporation of tear film
- Increasing humidity
- Avoiding prolonged use of computes
- Repositioning workstations
- Wearing eye protection
- Warm compresses
What are pham for dry eyes?
- Artificial tear solution (substituted cellulose ethers)
- non medicated ophthalmic ointments
Examples of artificial tear solution API?
- Hydroxypropyl Methylcellulose
- Carboxymethylcellulose
- Polyvinyl Alcohol
- Propylene Glycol
- Polyethylene Glycol
- Povidone
- Glycerin
What are the counseling points of viscosity of artificial tears?
- Greater viscosity = prolonged ocular contact time
- Mild dry eye may benefit from less viscous
- More severe may benefit from more viscous
What are the counseling points of types of artificial tears?
- Solution
- Gel
- Ointment (can cause blurred vision, for bedtime)
What are the counseling points of contact weares of artificial tears?
Some ingredients will interact with rewetting drops and other contact lens care products
What types of preservatives are preferred by manufacturers?
benzalkonium chloride and benzethonium chloride
Why is benzalkonium chloride and benzethonium chloride a good preservative for drops?
- Stability
- Antimicrobial activity
- Long shelf life
- Toxic effect on the the tear film and the corneal epithelium
What are the counseling points of suspensions of artificial tears?
- Shake before use
- If using a suspension and another dosage form, use the suspension last, because it has prolonged retention time in the tear film.
What are the counseling points of combo solutions products of artificial tears?
Wait at least 5 minutes before instilling the next drop to prevent the first drop from being flushed away by the second
What are the counseling points of combo drops and ointments products of artificial tears?
Instill the drops at least 10 minutes before the ointment so that the ointment does not become a barrier to the drops penetration of the tear film or cornea
What is the hallmark of allergic conjunctivitis?
Pruritus
What are the common allergens?
- Pollen
- Dander
- Topical eye preparation
What is allergic conjunctivitis?
- a red eye with watery discharge.
- not impaired but may be blurred because of excessive tearing