Week 8 - Mood Disorders

Question 1

How long must symptoms be present in order to be diagnosed as a mood disorder?

Answer 1

Several weeks or longer

Question 2

What are the different types of depression?

Answer 2

Postpartum depression

Persistent depressive disorder (dysthmia)

Seasonal affective disorder

Psychotic depression

Depression related to medical conditions, medication or substance abuse

Question 3

What are the different types of bipolar?

Answer 3

Bipolar I

Bipolar II

Cyclothymia disorder

other or unspecified

Question 4

What is premenstrual dysphoric disorder?

Answer 4

Occurs 7-10 days before menstruation

Hormonal changes

Anger, irritability , tension, decreased interest in usual activities , sleep problems

Question 5

What is intermittent explosive disorder”

Answer 5

Unwarranted anger

Out of proportion to situation

Question 6

How many people in low and middle-income countries do not receive treatment for depression?

Answer 6

76-85%

Question 7

What are some barriers to effective care of depression?

Answer 7

Lack of resources

Lack of trained health-care providers

Social stigma

Inaccurate assessment

Question 8

What are some psychological treatments for moderate and severe depression?

Answer 8

Behavioural activation

CBT

Interpersonal psychotherapy

antidepressants

• serotonin reuptake inhibitors (SSRIs)
• tricyclic antidepressants (TCAs)

Question 9

What are the different medical treatments for depression?

Answer 9

Selective serotonin reuptake inhibitors (SSRIs)

Serotonin and noradrenalin reuptake inhibitors (SNRIs)

Tricyclic antidepressants (TCAs)

Noradrenaline-serotonin specific antidepressants (NaSSAs)

Noradrenalin Reuptake inhibitors (NARIs)

Monoamine oxidase inhibitors (MAOIs)

Question 10

What are the different types of tricyclic antidepressants?

Answer 10

x

Question 11

The SNRIs drug class effects noradrenaline and serotonin. How can we tell the difference between drugs in that class?

Answer 11

5HT:NE reuptake inhibition ratio

Question 12

What is Electro convulsive therapy (ECT)?

Answer 12

• Rapidly relieves symptoms

Question 13

What is ketamine therapy?

Answer 13

• originally for anaesthetic
• Lower doses are very effective for depression
• Rapid
• Not permanent

Question 14

Describe the neuropharmacology of ketamine depression treatment.

Answer 14

x

• Less GABA (inhibition)
• Less glutamate excitation