Week 8 - biguinides Flashcards

1
Q

Glucophage

A

Metformin

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2
Q

How does metformin lower blood sugar?

A

allows for sugar to enter cells, improves tolerance

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3
Q

What are the indications for metformin?

A

t2d

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4
Q

What are the adverse effects for metformin

A

GI UPSET, metallic taste, weight loss

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5
Q

What are the drug interactions for metformin

A

affects contrast media, alcohol

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6
Q

What is the boxed warning?

A

lactic acidosis

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7
Q

Contraindications?

A

renal impairment (severe >30mg) and elderly patients > 80

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8
Q

What can be done about GI effects?

A

switch to XR to minimize

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