Week 8- Basal And Limbic Flashcards
List components of basal ganglia
• Caudate nucleus• Putamen•
Globus pallidus (externus and internus)•
Subthalamic nucleus and• Substantia nigra
Where is putamen located
Central of basal ganglia
Where is nucleus accumbens
Inferior and anterior of basal ganglia
Superior section to amygdala
Where is lateral ventricle
Posterior and behind cellular bridges
Looks like helicopter plant
Where is amygdala
Inferior on basal ganglia. Most anterior inferiority
Anterior to tail of caudate (at end of tail)
List functions of basal ganglia
• Control of voluntary movements (facilitates and/or inhibits motor activity)•
Determine how rapidly a movement is to be performed and how large themovement must be•
Decrease muscle tone and inhibit unwanted muscular activity•
Regulate the muscle tone and thus helps in smoothening the voluntarymotor activities•
Control automatic associated movements, like swinging of arms duringwalking Pyramidal Tract
Name excitatory neurotransmitter
GLUTAMATE
Name inhibitory neurotransmitter
GABA
What is direct pathways
Initiates movement (increase motor activity)
Comes straight into thalamus
Motor cortex
Striatum
Internus
Thalamus
What is MSIT used for and what does it stand for
Shows the direct pathway for gLUTAMATE
Motor cortex
Striatum
Internus
Thalamus
What is the indirect pathway
• Terminates movement (inhibits/ decreases movement)•
MS EN IT (Mnemonic)or• Comes Straight,Exits, then Sidesteps Into Thalamus-
Motor Cortex-
Striatum-
Externus-
Nucleus (Subthalamic)- Internus
-thalamus
What is MS EN IT used for and what does it stand for
Indirect pathway
Motor cortex
Striatum
External
Nucleus (subthalamic)
Internus
Thalamus
What turns on motor cortex and what turns it off
Direct = turns on motor cortex
Thalami’s motor planning
Indirect= turning off motor cortex
Activation of inhibition
list clinical aspects for direct and indirect pathways
• Tremors, Athetosis, Chorea•
Parkinson’s disease• Huntington’s disease• Tourette’s syndrome
What is athetoid
Involuntary movements
Slow and tithing sitar muscle and extremities