Week 8 Flashcards
Define symbiosis
To live together in a relationship which is mutually beneficial to the host and the microbe, or harmful to the host.
Define mutualism
Both members benefit from the symbiotic relationship and in some cases need each other for survival.
Define commensalism
One of the organisms in he symbiotic relationship benefits without affecting the other.
Define parasitism in terms of symbiosis.
A parasite benefits from its host without harming it
What type of relationships do microbiota in the normal flora have with the body?
Mutualistic and commensal
How many different types of microbiota are in the normal human flora?
400-1000
What are the 2 types of Indigenous microbiota?
Resident microbiota
Transient microbiota
What are indigenous microbiota?
They reside inside the body but rarely cause disease.
What are resident microbiota?
They are specially adapted t live in the body and are unique to each individual.
What is the main function of resident bacteria?
Compete out foreign bacteria.
How long can transient microbiota survive in the body for ?
Hours to months
Why can’t transient microbiota survive in the body long term?
There is alot of competition from other microorganisms.
They are often eliminated by the body’s immune system.
Affected by chemical and physical changes in the body.
What are opportunistic pathogens?
An infection caused by a pathogen that takes advantage of an opportunity that is not usually available.
Give examples of circumstances which may allow opportunistic pathogens to cause disease.
Immune suppression
Changes in normal microbiota
Incorrect location
Describe the presence of microbiota in the nose
Very unique microbiota because it is cooler than the rest of the respiratory system.
Describe the presence of microbiota in the trachea and bronchi
Sparse
Describe the presence of microbiota in the alveoli
No microbiota present
Describe the presence of microbiota in the vagina
Change as acidity changes in the vagina during the menstruations cycle.
Why can’t extensive colonisation of microbiota occur at the urethra?
The flow of urine prevents this
Why are there few microbiota in the eyes compared to the skin?
They are washed away by tears.
What prevents a foetus having any microbiota?
The presence of the amniotic fluid and use of the mothers immunity.
When the amniotic sac breaks, how does microbiota enter a baby?
Enters the mouth and nose of the baby via the birth canal.
At what stage can microbiota begin to enter the intestines of a baby?
Once it has consumed its first meal.
How quickly are resident microbiota established on a human body?
Within the first months of life
Define Pathogenicity
The ability to cause disease
Define Virulence
A measure of pathogenicity
Define contamination
The mere presence of microorganisms in or on the body.
Define infection
Invasion of the body by a pathogen
Define pathogen
A microorganism with the ability to cause disease.
What are virulence factors?
A variety of traits that interact with a host and enable the pathogen to enter, adhere, gain access to nutrients and escape detection from the immune system.