week 7: circulation - blood, heart Flashcards

1
Q

what are three function of the circulatory system

A

transport, regulation, protection

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2
Q

what are 4 structures that are part of the circulatory system

A

heart, arteries, veins, capillaries

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3
Q

what is blood composed of

A

plasma and cells

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4
Q

what cells are in blood?

A

erythrocytes (red)
leukocytes (white)
platelets

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5
Q

what substances are transported in blood

A

nutrients, waste products, respiratory gasses, hormones

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6
Q

what do red blood cells transport

A

oxygen

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7
Q

what do white blood cells, leukocytes, do?

A

function in defence.

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8
Q

what are platelets

A

fragments of cells that are involved in clotting

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9
Q

what is an erythrocyte?

A

red blood cell

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10
Q

how many molecules of oxygen does each molecule of hemoglobin contain

A

4

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11
Q

________ is a complex protein made up of four protein strands. iron is used to form heme groups.

A

hemoglobin

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12
Q

what is hematopoiesis

A

formation of blood cells

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13
Q

what are the three phases in the developmental pathway of red blood cell production

A

phase 1) ribosome synthesis
phase 2) hemoglobin accumulation
phase 3) ejection of nucleus

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14
Q

what is the lifespan of red blood cells

A

4 months

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15
Q

what is erythropoietin and what does it do

A

erythropoietin is a hormone produced in the kidneys that stimulates the production of red blood cells in red bone marrow.

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16
Q

what hormone is produced in the kidneys and stimulates production of red blood cells in red bone marrow

A

erythropoietin.

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17
Q

what are the 5 main types of leukocytes

A

– monocytes,
– neutrophils,
– basophils,
– eosinophils,
– Lymphocytes

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18
Q

what are the 4 possible blood groups

A

A, B, AB, O

19
Q

what is Landsteiner’s rule

A

individuals will form immune antibodies to ABO blood group antigens they do not possess.

20
Q

what are the two types in the Rh blood group
what does this determine

A

Rh positive have the antigens present on the red blood cell surface

Rh negative do not

determines whether the blood type is positive or negative.

21
Q

what blood type is a universal donor

22
Q

what blood type is universal recipient and can receive any blood type?

23
Q

what does hemostasis mean

A

prevention of blood loss

24
Q

what are the 4 steps in hemostasis?

A
  1. vessel injury
  2. vascular spasm
  3. platelet plug formation
  4. coagulation
25
what are platelets derived from?
megakaryocytes.
26
what is the lifespan of platelets
about 10 days .
27
during blood clotting what is converted into what?
prothrombin is converted into thrombin fibrinogen is converted into fibrin.
28
what is the implication of thromboembolic disorder
undesirable clot formation (thrombus)
29
what might prevent the formation of normal blood clots
bleeding disorder
30
what is a thrombus
a blood clot that persists in an unbroken blood vessel may cause an obstruction leading to tissue death
31
what is an embolus
a thrombus (blood clot) that is freely flowing in the circulatory system
32
what can prevent thromboembolic disorders
anti coagulants aspirin, heparin, warfarin
33
what type of disorder is thrombocytopenia
thrombocytopenia is a BLEEDING DISORDER
34
what are some implications of thrombocytopenia
too few platelets causes spontaneous bleeding
35
how is thrombocytopenia treated
treated with a transfusion of concentrated platelets.
36
what is one symptom of hemophilia
prolonged bleeding
37
what is the role of the right side of the heart. (right atrium and right ventricle)
Right atrium receives deoxygenated blood from body; delivers blood to right ventricle, which pumps blood to lungs
38
what is the role of the left side of the heart (left atrium and left ventricle)
Left atrium receives oxygenated blood from lungs; delivers blood to left ventricle, which pumps blood to rest of the body
39
what are the two types of valves in the heart
1. Atrioventricular 2. Semilunar
40
what are the two different atrioventricular valves called? and what side are they on?
bicuspid (left side) tricuspid (right side)
41
what are the two different semilunar valves called and what side are they on?
aortic (left side) pulmonary (right side)
42
what components are part of the blood vessels (artery and vein)
tunica externa tunica media tunica intima lumen
43
what components make up the structure of the capillary
endothelial cells and lumen.
44
what is atherosclerosis
LDL cholesterol forms plaques in arteries triggering inflammation.