Week 6-Basal Ganglia Flashcards

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1
Q

The Dorsolateral striatum is made up of the _____ and ____

A

Caudate and putamen

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2
Q

The ventral striatum is made up of the ___ and ___

A

nucleus accumbens and olfactory tubercle

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3
Q

What are the 6 parts of the basal ganglia?

A

globus pallidus, dorsal lateral striatum, ventral striatum, ventral pallium, substania nigra, and subthalamic nucleus

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4
Q

What is Hyperkinesia?

A

spontaneous movements that can not be voluntarily controlled

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5
Q

What is Hypokinesia?

A

marked by a paucity of movements, although the motivation and muscular ability is intact

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6
Q

what types of movements occur in Chorea?

A

spontaneous “dance like” movements (Huntington’s chorea)

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7
Q

what kind of movements occur during Athetosis and where?

A

a writhing combination of movements (most often of the hands)

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8
Q

What happens during Dystonia?

A

joint or postural freezing due to antagonistic coactivation; idiopathic torsional dystonia; spasmodic torticollis

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9
Q

What kind of movements happen during Ballismus?

A

rapid flailing movements of the extremities

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10
Q

What is a Tic?

A

similar to chorea but single movements repeat, not random

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11
Q

The loss of what kind of neurons in what area is impacted in the nigrostriatal pathway?

A

Dopaminergic neurons in the substantia migration pars compact

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12
Q

What is a tremor?

A

Involuntary rhythmic of agonist/antagonist muscles of the upper extremity, lower extremity or face

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13
Q

What is rigidity?

A

This usually manifests as complaints of muscle stiffness

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14
Q

What is bradykinesia?

A

Slow movement, difficulty initiating and carrying out purposeful movements

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15
Q

What is postural instability?

A

Problems with standing or walking or impaired balance and coordination due to loss of balance

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16
Q

What are some non-motor signs and symptoms of PD?

A

Cognitive impairment
Mood disorders
Problems sleeping
Low blood pressure
Constipation