Week 5- Meiosis- Holy Flashcards
What are the two major functions of meiosis
2 functions of meiosis → create haploid cells and increase genetic diversity
Compare meiosis and mitosis
Mitosis produces 2 identical daughter cells, meiosis produces 4 different haploid cells. Meiosis undergoes 1 S-phase with 2 M-phases, and they have pairing of homologous chromosomes with crossing over
What are germ cells called prior to meiosis, after the first meiotic division, and after the second meiotic division?
Germ cells prior to meiosis → Primary **cyte
After 1st meiotic division → Secondary **cyte
Second meiotic division → Males = spermatids, Females = mature egg
What are the two ways genetic diversity is generated in meiosis?
Genetic diversity → homologous recombination and independent assortment
What is homologous recombination (crossing over)?
homologous recombination → when 2 parts of homologous chromosomes exchange genetic information
What is random assortment?
Random assortment → when there is no order as to which chromosome (maternal or paternal) gets lined up on each side of the M plate to be pulled apart.
Differentiate between haploid, diploid, and tetraploid.
Haploid = 1 copy of chromosome, Diploid = 2 copies of chromosome, Tetraploid = 4 copies of chromosome
What is nondisjunction?
Nondisjunction → failure of chromosomes to separate accurately in anaphase, can happen in meiosis I or II or mitosis
order of event for males
germ cell ⇒ spermatogonia ⇒ highly mitotically active ⇒ TONS of spermatogonia ⇒ birth ⇒ puberty ⇒ speratogonia can keep reproducing mitotically or ⇒ primary spermocyte ⇒ meiosis I ⇒ secondary spermocyte ⇒ meiosis II ⇒ 4 haploid spermatids
order of events for females
germ cells: oogonia ⇒ highly mitotically active ⇒ TONS of oogonia ⇒ primary oocytes ⇒ meiosis I ⇒ arrest in prophase I ⇒ birth ⇒ stay in G0 state until puberty ⇒ handful of primary oocytes get stimulated each cycle to finish meiosis I ⇒ 1 polar body and one secondary oocyte ⇒ secondary oocyte either sloughs off if it is not fertilized or ⇒ gets fertilized ⇒ finish meiosis II which sperm invaginates
names of male PGC derivatives
PGC ==> spermatogonia ==> primary spermocytes ==> secondary spermocytes ==> spermatids
names of female PGC derivatives
PGC ==> oogonia ==> primary oocytes ==> secondary oocytes ==>
shugoshin
protein that makes sure sister chromatids remain together during anaphase I