Week 4A - need to read slides instead Flashcards
1
Q
How do we determine the cause of disease?
A
- Infectious?
- Genetic?
- Environmental?
2
Q
When was feed ban introduce for cows
A
1988
3
Q
When was specified bovine offals (SBO) ban
A
1990
4
Q
How disinfect samples containing PrPsc
A
– Radiation resistant
– Autoclaving resistant
– Formaldehyde can inactivate prion
5
Q
What are the limitation for Koch’s postulates
A
• The micro-organism is difficult or impossible
to grow in pure culture (such as the one that
causes leprosy)
• There is no suitable animal model of infection
(generally not an issue for veterinary
pathogens)
• Some micro-organisms only cause disease in certain situation
6
Q
What are prions
A
Proteinaceous Infectious Particle
– There is no genetic material (no DNA or RNA)
7
Q
What is a knock-out mice
A
A mouse where PrP are removed
