Week 4 vavlular and Vascular Lecture Flashcards
What does stenosis mean in valvular disease?
-Valve opening is narrowed
-blood can’t move forward properly
What is regurgitation in valvular disease?
valve fails to close properly and there is blood backflow
What side of the heart do valve disorders more frequently occur?
Left side of heart
(Lt receives from lungs, pumps out to body)
what are commonly heard upon ascultation with valvular disease?
murmurs
What is Mitral Stenosis?
Blood can’t move well from left atrium to L ventricle (narrow)
In mitral stenosis where does blood back up to and what does it cause ?
L atrium and lungs
atrial enlargement/hypertrophy
pulmonary congestion
What is a later stage of mitral stenosis and what does it cause?
back up to R ventricle
Rt sided HF
What are the major symptoms of mitral stenosis?
- SOB
- dyspnea upon exersion
- hemoptysis
- A fib
- stroke (emboli due to blood stasis from afib)
- eventually Rt sided HF (backs up into system- edema, JVP)
What is mitral regurgitation?
-valve doesn’t close properly
- blood flows back to Lt atrium and then goes back into Lt ventricle so there’s too much blood in there
What can mitral regurgitation result in?
Shock
dyspnea
What can mitral regurgitation lead to?
Rt. sided HF (JVP, peripheral edema)
What is mitral prolapse?
valve leaflets enlarge and prolapse into the atrium
Mitral prolapse is usually asymptomatic but patients can eventually feel what symptoms?
- chest pain
- exercise intolerance
- dysrhythmias
What is aortic stenosis?
Obstruction of blood flow between left vent and aorta (not atrium)
What does Aortic stenosis cause?
L vent hypertrophy
decreased CO
What are the classic symptoms of Aortic stenosis?
syncope
angina
dyspnea upon exertion
What med should we be cautious to give to people with aortic stenosis and why?
Nitro
b/c preload has to be maintained in order to force the valve open
When is surgery done for someone with aortic stenosis?
When the valve is less than 1cm = <1 cm
what is aortic regurgitation?
valve doesn’t close completely
blood backs up from the aorta (not atrium) to Lt vent
What part of the heart mechanics does aortic regurgitation impact?
pumping action - ineffective
b/c Lt. vent. hypertrophies
What are the signs of aortic regurgitation ?
low CO
hypotension (low BP)
Shock
PROFOUND DYSPNEA
angina
What are the 5 points of data we collect (Assessment) for someone with valvular heart disease?
- family HX
- crackles - pulmonary congestion
- murmurs - heart sounds/pulses
- peripheral edema (pulses)
- decreased CO - perfusion to organs such as kidneys
What are the 3 main PMHX things we should ask about in someone with valvular heart disease?
- previous rheumatic fever
- previous endocarditis
- hx of IV drug abuse
What are the 4 diagnostic tests for valvular heart disease and what do they test for?
- Echocardiography (structure & movment of heart) - ultrasound of heart
- Exercise tolerance test (determines severity)
- Chest xray (atrial and vent. enlargement)
- EKG (dysrhythmias)
What are 5 non-surgical interventions for someone with valvular heart disease?
- drug therapy and rest
- prevent exaacerbations of PE, thromboembolsim and endocarditis
- anticoagulant therapy (warfarin)
- antidysrhythmic drugs or cardioversion (if Afib)
- treat HF if it develops
What are 4 procedural/surgical interventions for people with valvular heart disease
- balloon valvuloplasty
- TAVR (transcatheter aortic valve replacement)
- Valve repair
- Valve replacement
What’s a major concern for someone with a mechanical valve?
Thromboembolism
- life long anticoagulants and blood monitoring
What are we worried about with biologic valve?
calcification
What valve cannot be replaced with a biologic valve and why?
Aortic valve
b/c increase pressure
Which kind of valve replacement requires anticoagulants for life, Mechanical or biologic?
Mechanical valve only
what do we teach people with valvular disease?
- exercise plan to increase cardiac tolerance
- REST between activity
- Fluid overload - wt gain, perf. edema, crackles to lungs
- less salt - avoid caffeine
- O2 if needed
- prophylactic antibiotics b/f invasive surgery/diagnostic procedure/dentist
- no smoking
- mechanical valve = anticoags for life
- take meds
What is Cardiogenic shock?
HEART CAN’T PUMP d/t damage
emergency
What is Cardiogenic shock most often associated with?
acute MI
what is the big difference between cardiac shock compared to other shock?
RAPID fluid replacement can CAUSE FURTHER DAMAGE
What is the goal for someone with cardiogenic shock?
- restore blood flow to myocardium
- allow perfusion
What is infective endocarditis?
-Infection of heart valves and/or endocardial surface of the heart
- vegetations form
What is infective endocarditis caused by?
Bacteria (staph, strep) in blood stream
Viruses
Fungi
what conditions predispose someone to developing infective endocarditis?
- Prior endocarditis
- damaged valves
- IV drug use
- Hospital aquired bacteremia
- Rheumatic heart disease
How do infecting organisms enter the body leading to infective endocarditis?
-Oral cavity
-Skin rashes /lesions/abscesses
- infections (cutaneous, GI, GU)
- surgery or invasive procedures (IVs, CVADS)
Symptoms of infective endocarditis
- Low grade fever- infection
- Malaise - body fighting
- Chills - temp reg issues
- anorexia - GI affected
- back pain
- Headache
- weight loss
- Myalgia
- heart murmurs
Vegetations can fragment and migrate. What two types of embolism does it cause?
- Organ embolization
- Vascular embolization
Which embolization is more painful when a vegetation fragments or migrates?
organ embolization
What parts of the body/organs are affected in organ embolization?
Brain
Spleen
Kidneys
Lungs
GI tract
arms and leg vessels
What type of skin issues does Vascular embolization cause?
-Splinter hemorrhages (nails)
-Petichia
-Janeaway’s lesions (hands/feet)
-Roth’s spots (eyes)
What 2 lab assessments do we use for infective endocarditis?
-Blood cultures
-CBC might show increased WBC
What diagnostics are used for infective endocarditis?
echocardiogram - shows how well heart chambers are pumping
1. standard thoracic (ultrasound)
2. transesophageal echocardiogram (esophagus)
What do we monitor in people with infective endocarditis?
- fever
- decreased perfusion (LOC, low urine output)
- complications from vegetations (LOC, dyspnea, pain)
What types of emboli can form with vegetations?
- cerebral emboli
- pulmonary emboli
- renal emboli
What should patients do who have infective endocarditis ?
-avoid excessive fatigue
-rest before and after activity
-physical/emotional rest
What are the 2 things to determine with infective endocarditis?
- Cause (IV drug use, dental visit, procedure, valve disease)
- damage (bloodwork, CXray, ECG, EKG)