Week 4 - T2DM, PCOS Flashcards

1
Q

___% of is due to insulin resistance: T2DM and gestational

A

90%

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2
Q

Aboriginal: _x more likely at risk of getting diabetes

A

4x

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3
Q

Insulin produced by ____; triggered by ___ BG (blood glucose)

A

B-cells, triggered by HIGH glucose

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4
Q

Glucagon produced by ____; triggered by ___ BG

A

a-cells, triggered by LOW glucose

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5
Q

Normal blood glucose;
Fasted:
Post prandial:

A
  • 3.5-5 mmol/L (fasted)

- 5-7 mmol/L (1-2 hrs post meal/post prandial)

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6
Q

Long term glucose control of HbA1c (saturated w sugar):
Normal:
Elevated:

A
  • Hb A1c 4-6% is normal

- Hb A1c >7% is elevated

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7
Q

Type 1 Diabetes Mellitus is a deficiency of…

A

Insulin

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8
Q

Type 1 Diabetes Mellitus is when ______….?

A

B-cells are attacked and destroyed by the body’s own immune system

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9
Q

Gestational diabetes non modifiable and modifiable risk factors

A

Non modifiable:

  • genetics: age, family history, ethnicity
  • Previous Gd or large birth

Modifiable:
inactivity, high body fat, PCOS

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10
Q

People with diabetes are ___ times more likely to suffer heart attacks and strokes

A

4

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11
Q

Diabetes is the leading cause of preventable ____ in Australia

A

blindness

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12
Q

Kidney failure is ____ times more common in people with diabetes

A

3

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13
Q

Amputations are ___ times more common in people with diabetes

A

15

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14
Q

More than ___% of people with diabetes experience depression, anxiety and distress

A

30

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15
Q

Gangrene is…

A

Death of tissue in part of the body (foot amputees)

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16
Q

People with insulin resistance: IMTG is _____, which interrupts insulin signalling, stops ______ from migrating to cell surface, therefore not allowing ____ to get into cell = sugar remaining high in blood

A

high, GLUT-4, glucose.

17
Q

Exercise causes SNS activity, which _____ insulin

A

reduces
- GLUT4 translocation facilitated by muscle contraction

–> exercise improves insulin resistance

18
Q

What group had most improvement of T2DM with exercise?

A

Aerobic AND RT