week 4, reynolds-pka Flashcards

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0
Q

reynolds number greater than __ is the transition point between laminar and transitional flow

A

2000

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1
Q

reynolds number states that resistance to flow __ when flow becomes turbulent

A

increases

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2
Q

reynolds equation is _

A

velocity x density x tube diameter
/
viscosity

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3
Q

reynolds is proportional to v, d, d

A

velocity, diameter, density

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4
Q

reynolds is inversely proportional to v

A

viscosity

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5
Q

reynolds says that when flow is turbulent, _ determines flow

A

density

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6
Q

what property of a gas determines gas flow rate through a variable orifice flow meter at HIGH FLOW RATE

A

density

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7
Q

what property of a gas determines gas flow rate through a variable orifice flow meter at LOW FLOW RATE

A

viscosity

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8
Q

why would you give a person in status asthmaticus heliox?

A

reducing the density reestablishes laminar flow

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9
Q

bernoulli’s principle states that fluids in an area moving __ than the surrounding area possess __ pressure

A

faster

less pressure

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10
Q

an example of bernoulli

A

blowing on the top of a piece of paper lifts the paper

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11
Q

venturi effect is a _ effect, the velocity of a fluid _ as the cross sectional area _

A

jet
increases
decreases

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12
Q

laplace’s law states that as the structure (the radius) expands, the tension (force) in the wall of the structure increases. Give me an example

A

an aortic aneurysm is much more likely to rupture that a normal vessel because the radius of the aneurysm is LARGER, thereby increasing the tension in the wall to the “breaking point”

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13
Q

according to LaPlace, will a small capillary or a large vein better withstand high blood pressure? why?

A

the small capillary, because it has a smaller radius and thus lower wall tension

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14
Q

LaPlace’s math T=P x r

A

tension = pressure x radius

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15
Q

in sphere’s, the wall tension is increased __ as much as with cylinders

A

twice

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16
Q

in a surfactant DEFICIENT alveolus, wall tension is __ and __ of size

A

constant

independent

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17
Q

in a surfactant deficient lung, is the pressure greater in a smaller or larger alveoli?

A

smaller

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18
Q

for alveoli with normal surfactant, tension __ with __ in radius

A

increases

increases

19
Q

in a patient with adequate surfactant, because tension increases proportionally with radius, the pressure within the alveolus _

A

does not change

20
Q

chemical equilibrium means that most chemical reactions are __ and competing processes of reactions and product break downs occur __

A

reversible

simultaneously

21
Q

when a system reaches equilibrium, the concentrations of all the products and reactants (starting materials) remain _

A

constant

22
Q

LeChatelier’s principle states that if a system in equilibrium is subjected to a disturbance, it tends to change in a way that __ this disturbance

A

opposes

23
Q

in physiology, equilibrium is called _

A

homeostasis

24
Q

each molecule of hemoglobin can carry _ oxygen molecules

A

4

25
Q

increasing temperature favors endo- or exo-thermic processes?

A

endothermic

26
Q

when one of the reactants or products is a __, changing volume and/or pressure significantly impacts equilibrium reactions

A

gas

27
Q

when the partial pressure of oxygen is increased, the equilibrium shifts to the _

A

right

28
Q

the equilibrium constant(__) is the numerical description of that balance

A

K

29
Q

as K increases, the reaction tends to increasingly favor __

A

products

30
Q

as K decreases, the reverse reaction is more __

A

favorable

31
Q

Acids produce _ ions in aqueous solution, acids are proton _

A

H+

donors

32
Q

Bases produce __ ions in aqueous solutions, bases are proton _

A

OH-

acceptors

33
Q

what is the Bronsted-Lowry theory?

A

acids are proton donators, bases are proton acceptors

34
Q

what the __ is a hydronium ion?

A

heck

h3o+

35
Q

an amphoteric species can __ as either an acid or a base

A

behave

ex. water

36
Q

what is an important amphoteric species that helps maintain pH in the blood?

A

monohydrogenphosphate

37
Q

conjugated acid/bases

A

i don’t really get this so look it up

38
Q

strong acids dissolved in water are essentially __% ionized

A

100

39
Q

the strongest base is hydroxide ion (OH-), so a strong base ionizes __% to produce OH- ions

A

100

40
Q

examples of weak acids

A

barbiturates

propofol

41
Q

what are some weak bases?

A
all local anesthetics
all opioids
benzos
etomidate
ketamine
42
Q

the pH scale = the negative log of H+

A

each change of 1 pH unit means the hydrogen ion concentration is changing by a factor of 10

43
Q

what is the pH of a liter of water?

A

7

44
Q

A large value of Ka means a __ acid

A

stronger

45
Q

A large Ka will have a __ pKa

A

small

46
Q

the sum of the pKa and pKb of the conjugate acid-base pair will be 14. So an acid with a pKa of 4 has a conjugate base with a pKb of _

A

10