Week 4 Lecture Content Flashcards
Which of the following best explains why humans are evolutionarily predisposed to weight gain?
a) We evolved to store fat during times of plenty as a buffer against potential famine
b) We evolved to prefer the taste of high-calorie foods
c) We evolved to have a slow metabolism
d) We evolved to be less physically active
a) We evolved to store fat during times of plenty as a buffer against potential famine
What is the BMI threshold for obesity?
a) >20
b) >25
c) >30
d) >35
c) >30
Which measure is considered potentially better than BMI for assessing obesity-related health risks?
a) Body fat percentage
b) Waist circumference
c) Hip-to-waist ratio
d) Skinfold thickness
b) Waist circumference
“Waist circumference may be a better measure, as visceral fat is better correlated to obesity-related health risks.”
Which type of diabetes is more closely related to obesity and bariatrics?
a) Type I diabetes
b) Type II diabetes
c) Gestational diabetes
d) Latent Autoimmune Diabetes in Adults (LADA)
b) Type II diabetes
In the Plagemann et al. study, what correlated with methylation tags on the Insulin Receptor Promoter (IRP) gene in baby rats?
a) Underfeeding
b) Normal feeding
c) Overfeeding
d) Fasting
c) Overfeeding
“If a baby rat is overfed early in life, this correlates with methylation tags on the Insulin Receptor Promoter (IRP) gene.”
According to the lecture, which of the following is NOT one of the three major reasons for the sudden increase in global obesity?
a) Inactivity
b) Increased portion sizes
c) Rise of highly processed foods
d) Increased stress levels
d) Increased stress levels
According to the Titos et al. study, what effect did dietary proteins have on flies and mice?
a) Made them more active
b) Made them less arousable from sleep
c) Increased their appetite
d) Decreased their lifespan
b) Made them less arousable from sleep
Which of the following is NOT a term used to describe a drug’s action?
a) Agonist
b) Antagonist
c) Inhibitor
d) Accelerator
d) Accelerator
What is the mechanism of action for orlistat (Xenical™)?
a) Serotonin reuptake inhibitor
b) Lipase inhibitor
c) Appetite suppressant
d) Metabolism booster
b) Lipase inhibitor
Which of the following is a potential drug target that, in theory, should increase hunger?
a) Leptin receptor agonist
b) Ghrelin receptor agonist
c) PYY3 agonist
d) CCK agonist
b) Ghrelin receptor agonist
Which type of bariatric surgery both restricts food intake and reduces nutrient absorption?
a) Gastric band
b) Sleeve gastrectomy
c) Gastric bypass
d) Gastric balloon
c) Gastric bypass
Malabsorptive + restrictive procedure.
What is a potential issue with Deep Brain Stimulation (DBS) for treating obesity?
a) It’s too expensive
b) It causes significant weight gain
c) It has given very mixed results when targeting the hypothalamus
d) It’s not invasive enough
c) It has given very mixed results when targeting the hypothalamus
Which of the following is NOT mentioned as a way the government could promote healthy eating?
a) Implementing taxes on unhealthy foods
b) Banning all processed foods
c) Subsidizing healthy foods
d) Restricting junk food advertising
b) Banning all processed foods
