week 4- ionising radiation Flashcards

1
Q

name 2 sources of ionising radiation

A

natural
artificial

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2
Q

list natural sources of radiation

A

Cosmic Radiation, Animals, Rocks, Buildings, Soil, Plants, Food, Water,People, Radon Gas

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3
Q

list artificial radiation sources

A

X-Ray Machines [ Medical Imaging ], Nuclear Power, Nuclear Missiles,Nuclear Weapons Testing

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4
Q

name characteristics of ionising radiation

A

Penetrating [ absorbed and scattered in a medium ]

Invisible [ to the eye ]

Reduces in intensity [ I ] with Half-Value Layer and Inverse Square Law

Can cause radiation-induced tissue damage / biological effects

Radioactive materials [ isotopes ] have activity [ half-life]

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5
Q

what is half value layer

A

is the thickness of a substance which will transmit one ½ of the intensity of the radiation incident upon it

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6
Q

define half lfe

A

The time taken for half of the atoms todecay is known as the half-life

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7
Q

state radiation safety principles

A

Time= The amount of radiation exposure depends directly (linearly) on the time spent near thesource of radiation. The radiation dose can be reduced by limiting exposure time.

Distance= The amount of radiation exposure depends on the distance from the source of radiation.

Shielding= If the radiation source is too intensive (and the time or distance do not provide sufficientradiation protection) then shielding can be used.

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8
Q

what is radon gas

A

It is a radioactive, colourless, and tasteless gas

It is formed by the radioactive decay of small amounts ofuranium that occur naturally in all rocks and soils.

 Every building contains radon but the levels are usually low

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9
Q

what is alpha decay

A

Alpha decay [α-decay] is the spontaneous emission of an alpha particle from a nucleus. Itconsists of two protons and two neutrons tightly bound together [ a helium nucleus ]

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10
Q

what is radioactive decay

A

Radioactive decay is the process by which an unstable atomic nucleus loses energy byemitting radiation, such as an alpha particle, a beta particle, or a gamma ray

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11
Q

what is beta decay

A

Beta decay [ β-decay ] is the spontaneous emission of a fast-moving particle with the mass ofan electron from a nucleus

Negative and positive beta particles are produced by the decay of either a proton or a neutron

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12
Q

name 2 types of radiation induced tissue damage

A

direct
indirect

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13
Q

what is direct radation induced tissue damage

A

action or damage – ionisation of macromolecules

DNA, RNA, Proteins, Enzymes

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14
Q

what is indirect radation induced tissue damage

A

action or damage – free radicals produced by ionisation of water

H+ OH very radioactive

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15
Q

free radicals can recombine to form what?

A

hydrogen peroxide and a hydroperoxyl radical, both of which are highly reactive and produce biological damage

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16
Q

what will the transferrerl of excess energy do

A

break chemical bonds of other molecules

17
Q

when is strand break problematic

A

usually repaired

if not repaired, effect is dependent upon where the damage has occurred

Protein Production [Okay]
Cell Division [Problematic]

double strand break inhibits tumour supressor gene

18
Q

what does breakage of macromolecules lead to

A

breakage of chemical bonds
-inappropriate chemical reactions
-abnormal replication/ cell death
-damagte to reproductiove cells

19
Q

what is Linear Energy Transfer

A

how much energy is transferred per unit length

20
Q

name 2 biological effects of ionising radiation

A

Deterministic Effects
Non-cancer damaging effects that will definitely result fromhigh dose radiation

 Stochastic Effects (Chance / Probabilistic)
 Cancer and genetic effects that may result or develop

21
Q

if a somatic cell is iorridated, what is there a chance of

A

radiation induced malignancy (cancer) to develop

22
Q

what is an absorbed dose

A

Absorbed Dose is the energydeposited per unit mass and ismeasured in joules per kilogram[J.kg-1]

It is given the special name ofgray with the SI unit symbol Gy

23
Q

what is an equivalent dose

A

Equivalent Dose is a measure of the radiation dose to tissue with an allowance for the different relative biological effects for different types of ionising radiation

Sv

24
Q

give an equation to work out equivelent dose

A

Equivalent Dose =Absorbed Dose ×Radiation Weighting Factor (WR

25
Q

how do we work out absorbed dose

A

times by photons (1)

26
Q

how do we work out absorbed dose

A

tissue or organ times alpha particles

26
Q

what is the effective dose

A

he effective dose is used to compare the stochastic risk of non-uniform exposure to radiation. Body tissues react differently to radiation and cancer induction occurs at a different rate of dose in different tissues.

Effective dose is measured using the sievert (Sv)

Effective Dose =Σ [ Equivalent Dose ×Tissue Weighting Factor (WT)

26
Q

what does alpha radiation consist of and what is it stopped by

A

helium-4 nucleus and iseasily stopped by a sheet of paper

26
Q

what does beta radiation consist of and what is it stopped by

A

high-energy electrons orpositrons is halted by an aluminium plate

26
Q

what does gamma radiation consist of and what is it stopped by

A

high-energy photon emitted by thenucleus which can eventually be absorbed as it penetratesa dense material, such as lead [Pb]