Week 4 - Important concepts Flashcards

1
Q

pervasive and sustained emotion that colours one’s perception of the world and how one functions in it

A

mood

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2
Q

recurrent disturbances or alterations in mood causing psychological distress and behavioural impairment

A

mood disorder

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3
Q

Mood disorders have alterations in mood, but not in what?

A

Thought or perceptions

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4
Q

loss of interest in previously enjoyed activities

A

anhedonia

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5
Q

absent or nearly absent affective expression

A

flat affect

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6
Q

significantly reduced intensity of emotional expression

A

blunted affect

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7
Q

mildly reduced in range and intensity of emotional expression

A

restricted or constricted affect

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8
Q

discordant affective expression accompanying speech content or ideation

A

inapprpriate affect

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9
Q

varied, rapid and abrupt shifts in affective expression

A

labile affect

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10
Q

What are the primary mood disorders?

A

Unipolar - MDD

Bipolar - manic-depressive disorder

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11
Q

What is the general clinical course for MDE?
What is the mean age of onset?
How long can an untreated episode last?
What is the most serious complication?

A

over time, episodes are more frequent, severe and longer in duration
Mean age of onset is 40 yrs
An untreated episode can last 6-13 months
Suicide is the most serious complication

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12
Q

Milder, but more chronic form of MDD

Depressed mood, most days for over 2 yrs with 2+ symptoms

A

Dysthymic disorder

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13
Q

something bad happens in life and you experience a state of depression which ultimately resolves

A

transient depression

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14
Q

MDE epidemiology
What proportion of the population will experience at least one MDE in their life?
Which gender is affected more in adolescence?

A
half
females (2x more than adolescent males)
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15
Q

When was the Brown and Harris model of depression developed?

What is the underlying assumption?

A

1986

certain “vulnerability factors” can interact with provoking agents to increase the risk of depression

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16
Q

What are the vulnerability factors of the Brown and Harris model of depression?

A

Early maternal loss
lack of confiding relationship
Greater than three children under the age of 14 at home
unemployment

17
Q

What is antidepressant choice based on?

A

Target symptoms and the client’s side effect profile

18
Q

What are first gen antidepressants?

A

MAOIs and TCAs

19
Q

Why are 2nd gen drugs used instead?

A

lower side effect profile and lower toxicity - safer in overdose

20
Q

often used as sleep aid in elderly

A

amitriptyline

21
Q

often given as it doesn’t impact sex drive

22
Q

interferes with SSRI’s – can lead to serotonin syndrome

A

St. john’s wort

23
Q

What is a manic episode characterized by?

A

Euphoria/elation
Expansive mood/grandiosity
Labile mood
(Hypersexuality)

24
Q

Less intensity than mania; mixed features

A

hypomanic episode

25
What is the difference between type 1 and type 2 bipolar disorder?
Type 1 - MDD and manic episodes | Type 2 - MDD and hypomania
26
How does bipolar disorder manifest in the elderly?
More neurologic abnormalities and cognitive disturbances
27
Bipolar epidemiology Prevalence? Onset?
0.2-0.6& | 21-30 yrs
28
What are the gender considerations for bipolar disorder?
no gender differences for bipolar I | Bipolar type II 5% greater in females = phenomenology, treatment and course
29
lithium carbonate and carbamezapine; often given with antidepressants to stabilize mood
mood stabilizers
30
Why are anticonvulsives often given for bipolar disorder?
Drugs work on the excitatory processes in the brain that are active in mania
31
What is the first line of treatment for manic-depressive disorder?
Lithium (carbonate)