Week 4 - Important concepts Flashcards

1
Q

pervasive and sustained emotion that colours one’s perception of the world and how one functions in it

A

mood

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2
Q

recurrent disturbances or alterations in mood causing psychological distress and behavioural impairment

A

mood disorder

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3
Q

Mood disorders have alterations in mood, but not in what?

A

Thought or perceptions

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4
Q

loss of interest in previously enjoyed activities

A

anhedonia

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5
Q

absent or nearly absent affective expression

A

flat affect

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6
Q

significantly reduced intensity of emotional expression

A

blunted affect

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7
Q

mildly reduced in range and intensity of emotional expression

A

restricted or constricted affect

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8
Q

discordant affective expression accompanying speech content or ideation

A

inapprpriate affect

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9
Q

varied, rapid and abrupt shifts in affective expression

A

labile affect

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10
Q

What are the primary mood disorders?

A

Unipolar - MDD

Bipolar - manic-depressive disorder

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11
Q

What is the general clinical course for MDE?
What is the mean age of onset?
How long can an untreated episode last?
What is the most serious complication?

A

over time, episodes are more frequent, severe and longer in duration
Mean age of onset is 40 yrs
An untreated episode can last 6-13 months
Suicide is the most serious complication

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12
Q

Milder, but more chronic form of MDD

Depressed mood, most days for over 2 yrs with 2+ symptoms

A

Dysthymic disorder

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13
Q

something bad happens in life and you experience a state of depression which ultimately resolves

A

transient depression

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14
Q

MDE epidemiology
What proportion of the population will experience at least one MDE in their life?
Which gender is affected more in adolescence?

A
half
females (2x more than adolescent males)
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15
Q

When was the Brown and Harris model of depression developed?

What is the underlying assumption?

A

1986

certain “vulnerability factors” can interact with provoking agents to increase the risk of depression

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16
Q

What are the vulnerability factors of the Brown and Harris model of depression?

A

Early maternal loss
lack of confiding relationship
Greater than three children under the age of 14 at home
unemployment

17
Q

What is antidepressant choice based on?

A

Target symptoms and the client’s side effect profile

18
Q

What are first gen antidepressants?

A

MAOIs and TCAs

19
Q

Why are 2nd gen drugs used instead?

A

lower side effect profile and lower toxicity - safer in overdose

20
Q

often used as sleep aid in elderly

A

amitriptyline

21
Q

often given as it doesn’t impact sex drive

A

Welbutrin

22
Q

interferes with SSRI’s – can lead to serotonin syndrome

A

St. john’s wort

23
Q

What is a manic episode characterized by?

A

Euphoria/elation
Expansive mood/grandiosity
Labile mood
(Hypersexuality)

24
Q

Less intensity than mania; mixed features

A

hypomanic episode

25
Q

What is the difference between type 1 and type 2 bipolar disorder?

A

Type 1 - MDD and manic episodes

Type 2 - MDD and hypomania

26
Q

How does bipolar disorder manifest in the elderly?

A

More neurologic abnormalities and cognitive disturbances

27
Q

Bipolar epidemiology
Prevalence?
Onset?

A

0.2-0.6&

21-30 yrs

28
Q

What are the gender considerations for bipolar disorder?

A

no gender differences for bipolar I

Bipolar type II 5% greater in females = phenomenology, treatment and course

29
Q

lithium carbonate and carbamezapine; often given with antidepressants to stabilize mood

A

mood stabilizers

30
Q

Why are anticonvulsives often given for bipolar disorder?

A

Drugs work on the excitatory processes in the brain that are active in mania

31
Q

What is the first line of treatment for manic-depressive disorder?

A

Lithium (carbonate)