Week 4 Flashcards
Define acquired language disorder
damage to the brain itself; typical or normal development up until damage occurs (TBI, brain tumour)
Define developmental disorder
begins prior to the emergence of language; can occur secondary to other disorders
ADS
Spectrum of early neruodevelopmental disorders of unknown cause characterised by abnormal development of brain circuitry essential for integrating social interaction and communicative skills
Red flags for ASD
lack of appropriate eye gaze, response to name , pointing, coordination of gaze & facial expression, repetitive movement
Define developmental lexical delays
children who have small vocabularies that are not attributable to poor hearing, low intelligence, brain damage or primary affective disorder
Language disorder vs delay
Delay: still developing normally but at a slower rate- will catch up. Disorder: abnormal language development
Definition and function of a neurone
The basis of the CNS. Continually adapting to environment. All communication within the brain is done via the neurones and their attachments
Definition and function of a soma
Define: most prominent part of the cell, filled with watery, salty K+ rich cytosol. Function: contains important organelles: Nuclues, Rough ER, Smooth ER, golgi apparatus and mitochondria, “mini-factory” to create proteins
Definition and function of a Neuronal membrane
Define: A barrier that encloses the cytoplasm. Function: studded with proteins (controls what enters and leaves the cell)
Definition and function of the Cytoskeleton
define & Function; non static internal scaffolding of neuronal membrane, three bones; Microtubules (transportation for proteins), Microfilaments (flexible allow for change of shape), Neurofilaments (hold axon together)
Definition and function of an axon
Define: Different from soma as ER doesn’t exist in the axon. Axon hillock -> axon proper -> axon terminal. Function: information exchange.
Definition and function of a dendrite
Define: the antennae of the neruon, Function: receives the information
Name and functions of the 4 different Glia Cells
- Astrocytes- fills space between neurons, regulates the environment around the nerve cell
- Myelinating Glia- Schwann Cell- provides layers of membrane that insulates the axon
- Ependymal cells- cell brith and migration
- Microglia- moves to site of injury, removes debris & regulates environment
Multiple Sclerosis
Demylination eventually causes the neurones to die, results in muscular weakness, tremors, impaired coordination & visual problems. Scars (plaques and lesions) appear in the white matter of the brain & spinal cord when reviewing an MRI
Name 5 protective layers of the brain
- skull, dura mater (hard wearing) , arachnoid layer (spider, sticky), pia mater (glad wrap) , subarachnoid space (filled with CSF)