Week 4 Flashcards

1
Q

develops if the supply of coronary blood cannot meet the demand of the myocardium for oxygen and nutrients.

A

myocardial ishmeia

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2
Q

most common cause of myocardial ishmeia

A

atherlosclerosis

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3
Q

chest pain caused by myocardial ischemia.

A

Angina pectoris

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4
Q

substernal chest discomfort, ranging from a sensation of heaviness or pressure to moderately severe pain

A

angina pectoris

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5
Q

Pain may radiate to the neck, lower jaw, left arm, and left shoulder
-Pallor, diaphoresis, and dyspnea
- relieved by rest and nitrates;

A

angina pectoris

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6
Q

-gradual luminal narrowing and hardening of the arterial walls
-associated with physical exertion or emotional stress.

A

stable angina

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7
Q

-transient ischemia of the myocardium that occurs unpredictably and almost exclusively at rest.

A

Prinzmetal angina (also called variant angina)

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8
Q

when does variant angina occur

A

at rest and randomly

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9
Q

Management of Reversible Ischemia

A

-increase delivery of oxygen
-omprove coronary artery blood flow and to -reduce myocardial oxygen consumption.

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10
Q

Myocardial Ischemia treamtnet

A
  1. Nitrates (nitroglycerin)-
  2. Beta Blockers-
  3. Calcium channel clockers (CCBs)
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11
Q

improve coronary blood flow and reduce myocardial demand by decreasing peripheral vascular resistance

A
  1. Nitrates (nitroglycerin)-
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12
Q

diminish catecholamine induced elevations of heart rate, myocardial contractility, and blood pressure

A
  1. Beta Blockers-
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13
Q

decrease the influx of calcium into myocardial cells and vascular smooth muscle cells
-modify SA and AV nodes

A

calcium channel blockers (CCBs)

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14
Q

procedure whereby stenotic (narrowed) coronary vessels are dilated with a catheter

A

Percutaneous coronary intervention (PCI)

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15
Q

atherosclerotic plaque has ruptured, and infarction may soon follow.

A

unstable angina

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16
Q

-occludes the vessel for no more than 10 to 20 minutes
-new onset angina, angina that is occurring at rest, or angina that is increasing in severity or frequency.

A

unstable angina

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17
Q

Unstable angina is precurssor
Infarction happens if last more than 20 mins

A

Unstable angina is precurssor
Infarction happens if last more than 20 mins

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18
Q

Subendocardial myocardial infarction

A

involves only one layer of the heart
the mysocradium

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19
Q

Transmural MI

A

-effects all 3 layers of heart
Transmural infarction usually causes marked elevations in the ST segments on ECG.
-immediate intervention

20
Q

Cardiac cells can withstand ischemic conditions for about ___–minutes before cellular death takes place.

21
Q

when ischemic injury is exacerbated once blood flow is restored

A

Reperfusion Injury
-involves the release of toxic oxygen radicals, calcium flux, and pH changes
-mitochonrdia death

22
Q

first symptom of acute MI is

A

usually sudden, severe chest pain

23
Q

heavy and crushing, such as an“elephant sitting on my chest.
-radiate to the neck, jaw, back, shoulder, or left arm.

A

myocardial infarction

24
Q

most commonly occluded artery and most associated with death after MI

A

left anterior descending artery (LAD)

25
most specific indicator of MI and should be obtained on admission to the emergency department
Cardiac troponin I
26
cTnI elevation is detectable
-2 to 4 hours after onset of symptoms -reaches peak at 48 hours
27
heart is unable to generate an adequate cardiac output such that there is inadequate perfusion of tissues or increased diastolic filling pressure of the left ventricle, or both.
heart failure
28
risk factors for heart failure
Ischemic heart disease and hypertension
29
which side of heart failure is most common
L sided
30
an ejection fraction of <40% and an inability of the heart to generate an adequate cardiac output to perfuse vital tissues.
systolic heart failrue
31
_____- are the result of pulmonary vascular congestion and inadequate perfusion of the systemic circulation
HFrEF Heart Failure with reduced ejection fraction
32
cardinal signs of CHF
dyspnea fatigue edema pulmonary edema hypotension or hypertension S3 gallop underlying CAD or hypertension
33
drugs for left sided heart failure
ACE inhibitors and beta blockers -Salt restriction, loop diuretics, and aldosterone-blockers such as spironolactone and eplerenone are effective in reducing preload and improving outcomes.
34
________- ventricular failure causes fluid to back up in the veins of the systemic circulation.
Right
35
R sided heart failure sxs
-Pitting edema in the ankles, feet, or lower back -Hepatomegaly / hepatic tenderness -jugular vein distention
36
Sinus Bradycardia
-less than 60 BPM -regular rhythm -fatigue, lightheadedness, dizziness, exercise intolerance, syncope or presyncope, worsening of anginal symptoms, worsening of heart failure, or cognitive slowing
37
Sinus tachycardia
->100 bpm -regular rhythm -dyspnea, chest pain, lightheadedness, dizziness, syncope, and presyncope.
38
Premature Ventricular Contraction (PVC)
-heartbeat is initiated by the Purkinje fibers rather than the SA node. -PVC occurs before a regular heartbeat, there is a pause before the next regular heartbeat -begign and don't need tx
39
most common sustained cardiac arrhythmia
Atrial Fibrillation
40
loss of atrial contraction and the rapidity and irregularity of the ventricular rate
Atrial Fibrillation
41
pulse rate >300 and on EKG usually no observable PR interval and QRS rate variable and rhythm irregula
Atrial fibrillation
42
Arrhythmias originating from the ventricular myocardium or His-Purkinje system are grouped under ventricular arrhythmia (VA)
ventricular fibrillation
43
ventricular rate of usually greater than 300 with discrete QRS complexes on the electrocardiogram (ECG).
ventricular fibrillation
44
extremely dangerous rhythm significantly compromising cardiac output and ultimately leading to sudden cardiac death (SCD).
VF
45
attacks of vasospasm in the small arteries and arterioles of the fingers and, less commonly, the toes
Raynaud’s
46
-pallor, numbness, and the sensation of cold in the digits -billateral -gin at the tips of the digits and progress to the proximal phalanges
Raynaud’s