Week 3.2.1: Predicting the Transition to Psychosis Flashcards
Early symptoms that precede the onset of a first episode of psychosis.
Prodromal Symptoms
These may appear up to five years before the first episode of psychosis.
Negative Attenuated Symptoms
These may appear about one year before the onset of psychosis.
Positive Attenuated Symptoms
Identifying individuals who are at high risk of developing psychosis before the onset of the disorder.
Clinical High Risk
Emphasized the importance of early treatment to prevent severe outcomes, such as institutionalization.
Henry Maudsley
A historical study published over 20 years ago, suggesting that certain symptoms precede the onset of psychosis.
ABC First Episode Study
Retrospective VS Prospective Studies
Retrospective studies identify symptoms after the onset, making it difficult to change the course of the disorder. Prospective intervention aims to identify high-risk individuals early.
What are the inclusion criteria for at-risk mental state?
- APS (Attenuated Psychotic Syndromes)
- BLIP (Brief and Limited Intermittent Psychotic Symptoms)
- GRD (Genetic Risk and Deterioration Syndrome)
Sub-threshold positive psychotic symptoms that are not severe enough to qualify as a frank psychotic disorder according to international diagnostic manuals like the ICD or DSM.
APS (Attenuated Psychotic Syndromes)
Short-lived episodes of psychosis lasting less than seven days and resolving without antipsychotic interventions
BLIP (Brief and Limited Intermittent Psychotic Symptoms)
Individuals with a first-degree relative affected by psychosis plus psychosocial dysfunction
GRD (Genetic Risk and Deterioration Syndrome)
Developed by: Professor Alison Yung in Melbourne, 20 years ago.
Interview Process: Involves asking several questions to assess the severity and frequency of attenuated positive psychotic symptoms.
Rating: Symptoms are rated based on severity (first row) and frequency (second row) in the CAARMS spreadsheet.
CAARMS (Comprehensive Assessment of At-Risk Mental State)
