Week 3 review

Question 1

nodes in viral infection

Answer 1

tender
firm
regular
not tethered
not associated with overlying inflammation (as opposed to bacterial infection)

Question 2

atypical lymphocytes, scalloping around red blood cells - what type of infection should you think about

Answer 2

viral

Question 3

EBV - serology: Ig__

Answer 3

M

Question 4

approach to leucocytosis

Answer 4

• what is the differential cell count?
• which cell type is abnormal?
• is there a stimulus?

Question 5

causes of neutrophilia

Answer 5

• bacterial infection
• inflammation
• trauma/post-op
• corticosteroids (redistribution)
• myeloproliferative neoplasms

Question 6

causes of lymphocytosis

Answer 6

• viral infections
• pertussis
• chronic lymphocytic leukaemia (clonal)

Question 7

in pancytopenia - reduced production (bone marrow failure), is inherited or acquired cause more common

Answer 7

acquired

Question 8

what are reed sternberg cells characteristic of

Answer 8

hodgkins lymphoma

Question 9

Ann Arbor staging - what is it used for

Answer 9

lymphoma

Question 10

B symptoms of lymphoma

Answer 10

fever
drenching night sweats
weight loss

Question 11

cytotoxic drugs: side effects

Answer 11

• bone marrow suppression
• gut mucosal damage
• hair loss

Question 12

when is peak incidence of hodgkins lymphoma

Answer 12

20-30s

Question 13

hodgkins lymphoma treatment if patient is not responding to chemotherapy

Answer 13

immunotherapy/stem cell transplantation