Transfusion

Question 1

how long can platelets be kept for

Answer 1

7 days

Question 2

at what temp are platelets stored

Answer 2

22 degrees Celsius

Question 3

what chromosome is the ABO gene expressed on

Answer 3

chromosome 9

Question 4

antisera

Answer 4

antibodies in a bottle

Question 5

agglutination positive vs negative

Answer 5

positive - clumps together in the tube

Question 6

indirect anti-globulin test (IAT) - addition of ________ to
plasma/ red cell suspension facilitates red cell
agglutination

Answer 6

anti-human globulin (AHG)

Question 7

when performing IAT before transfusing - with the plasma do you want to see agglutination?

Answer 7

no, we don’t want it reacting

Question 8

if someone has been transfused, can they still be a blood donor later?

Answer 8

nope

Question 9

indications for red cell transfusion

Answer 9

symptomatic anaemia Hb <70g/L (80g/L if cardiac disease)

major bleeding

Question 10

how many red cells should you transfuse for a stable non-bleeding patient

Answer 10

single unit of red cells and then reassess patient

Question 11

indications for platelet transfusion

Answer 11

prophylaxis in patients with bone marrow failure and very low platelet counts

treatment of bleeding in thrombocytopenic patient

prophylaxis prior to surgery/procedure in thrombocytopenic patient

always consider the cause before transfusion

Question 12

standard dose of platelet transfusion

Answer 12

one unit of platelets

Question 13

indications for FFP (Fresh frozen plasma) transfusion

Answer 13

• Treatment of bleeding in patient with coagulopathy (PT ratio >1.5)
• Prophylaxis prior to surgery or procedure in patient with coagulopathy (PT ratio >1.5)
• Management of massive haemorrhage
• Transfuse early in trauma
• NOT in absence of bleeding/ planned procedure