week 3 pharm Flashcards
SSRI’S
first line of long- term treatment for *depression, anxiety, OCD, PTSD, bulimia, & panic disorder
*2-3 WEEKS FOR FULL EFFECT
*citalopram
*escitalopram
*fluoxetine
*paroxetine
*sertraline
side effects of SSRI’S
*CITALOPRAM
*ESCITALOPRAM
*FLUOXETINE
*PAROXETINE
*SERTRALINE
sexual dysfunction
weight gain
adverse effects of SSRI’s
nausea / headache
anxiety
agitation
reduced appetite
insomnia
hyponatremia
when caring for a patient on tricyclic antidepressants..
AMITRIPTYLINE
*watch for ORTHOSTATIC HYPOTENSION
*increase fluid & fiber
*sugar less gum
MAOI’s foods to avoid
- phenelzine*
avoid TYRAMINE
no :
-cheese
-avocado
-beer/wine
-smoked meats
- liver
-fish
patients taking phenelzine are at risk for…
hypertensive crisis
*MAOI’s
adverse effects of buproprione
nausea/headache
dry mouth
insomnia
restlessness
constipation
gi distress
increase heart rate
SNRI’S
*VENLAFAXINE
*DESVENLAFAXINE
*DULOXETINE
*LEVOMILNACIPRAN
treats MDD & anxiety — long term
Venlafaxine, Desvelafaxine, duloxetine, & levomilnacipran adverse effects
SNRI’S
* serotonin syndrome
* hyponatremia (especially w older adults on diuretics)
sexual dysfunction
insomnia
nausea
weight gain
diaphoresis
adverse effects of ST John’s wort
*abdominal pain
*photosensitivity
*nightmares
skin rash
gi distress
increased heart rate
serotonin syndrome
serotonin syndrome symptoms
*increased temperature
*abdominal pain
restlessness
sweating
shivering
hyperreflexia
SSRI’s are contraindicated in
*citalopram, escitalopram, fluoxetine, paroxetine, sertraline
Ulcers
GI bleeds
Trazodone
adjunct for sleep & depression
suicide risk
adverse effect of Trazodone
priapism = painful erection
suicide risk
tricyclic antipdepressants
*Amitriptyline
*Doxepin
*Imipramine
*Notriptyline
highly cardio-toxic antidepressant
easy to overdose
side effects and amitriptyline
*TCA - amitryptline, doxepin, imipramine, & nortriptyline
**constipation
* urinary retention
dry mouth
blurred vision
photophobia
tachycardia
sexual dysfunction
adverse effects of TCA’s
amitryptyline, doxepin, imipramine, & nortryptyline,
*consitpation
*urinary retention
*orthostatic hypotension
* MI
*dysrhythmias
*heart block
paitents on TCA’s are
*amitryptyline, doxepin, imipramine, & nortryptyline
a high fall risk
*orthostatic hypotension
TCA’s are contraindicated in
*amitryptyline
MI
narrow angle glaucoma
BPH
seizures
MAOI’s
Phenelzine
Isocarboxazid
Tranylcypromine
Selegiline
*last medication to try for antidepressant
adverse effects of MAOi’s
*phenelzine
hypertensive crisis
n/v
confusion
diaphoresis
anxiety
blurry vision
foods to avoid on MAOI’s
*charcuterie board
dairy
avocado
deli meats beers
protein supplements
yeast
tyramine
MAOI”s are contraindicated in
cardiovascular diseases
liver diseases
headaches
surgeries
Bupropion
treats DEPRESSION & smoking cessation & weight loss
*seizures**
those who cant tolerate SSRI’s
Bupropion adverse effects
appetite suppression
seizures (contraindicated)
ketamine
controlled substance that targets suicidal ideation & used on aggressive patients & treatment resistant patients
IV & nasal spray
side effects of ketamine
dissociation
increased BP & hR
patients taking busiprone are at risk for
*serotonin syndrome
*falls = orthostatic hypotension
diphenhydramine & hyroxyzine
antihistamines used as antidepressants for clients with substance abuse disorders
**sedating & PRN ONLY
antidote for benzodiazepenes
flumazenile
busiprone interacts w
***ANXIETY
erythromycin
ketoconazole
grapefruit juice
st john’s wort
