Week 3: ADHD Basics & Epidemiology Flashcards

1
Q

Is ADHD real?

What is the evidence for this?

What 3 things is a diagnosis associated with?

Who consumes all the drugs?

A

Many have argues that ADHD is a product of western culture and pathologizing common mental experience and unrealistic expectations concerning children’s behavior or a product of the pharmaceutical industry promoting its interests

HOWEVER

The prevalence of ADHD is similar worldwide if you conduct thorough testing.

Presence of ADHD is associated with marked impairment:
Problems with peers (no friends)
Problems with school (failure)
Mortality (more likely to be in fatal accidents)

BUT

In the USA, 92-95% of ADHD medication is bought by the USA. So in NA this is way higher than the rest of the world.

For the purposes of this course, ADHD is real.

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2
Q

Core characteristics of ADHD

A

1) Inattention
Inability to sustain attention, especially for repetitive, structured and less-enjoyable tasks (can stick to stuff they like, video games)

2)
Hyperactivity/Impulsivity
Hyperactivity - inability to voluntarily inhibit dominant or ongoing behavior
Impulsivity - inability to control immediate reactions or to think before acting

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3
Q

DSM-5 Criteria (3 types)

A

Primarily inattentive: ADHD PI

  • At least 6 inattentive symptoms, fewer than 6 hyperactive symptoms
  • 17 or older; 5 inattentive symptoms, fewer than 5 hyperactive symptoms

Primarily hyperactive: ADHD HI

  • At least 6 hyperactive symptoms, fewer than 6 inattentive symptoms
  • 17 or older - at least 5 hyperactive, fewer than 5 inattentive

Combined - ADHD C

  • At least 6 hyperactive and at least 6 inattentive symptoms
  • 17 and older, 5 & 5

Reflects the fact that normatively, these symptoms decrease with age

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4
Q

DSM-5 Criteria (additional)

4 things

A

1) Symptoms must persist for more than 6 months
(this could be too small for young children who could be going through a phase)

2) There must be persistence (ongoing), impairment (must get in the way) and non-normative m(must be different from what we expect from a child of that age)

3) Several symptoms were present BEFORE 12 YEARS OF AGE
Used to be 7 in DSM IV
Could be diagnosed later but have to have symptoms before

4) Several symptoms are present in at least two settings
Typically home and school
Emphasizes that you need two people’s report (parent and teacher)

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5
Q

DSM-5 Criteria (Severity)

A

3 classifications

Mild:
Few, if any, symptoms in excess of those requires to make the diagnosis. Symptoms cause minor impairment in social or occupational functioning

Moderate:
Symptoms of functional impairment between mild and severe are present

Severe:
Many symptoms in excess of those required to make the diagnosis are present or several symptoms that are particularly severe. Or the symptoms result in marked impairment socially or occupationally.
-Such a child could not be in a regular classroom

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6
Q

Categorical vs dimensional

What says it is categorical?
What says it is dimensional?

A

DSM says ADHD is categorical

Research says it is dimensional

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7
Q

Assessment of ADHD:

What do you use?
Who do you ask?
Are there differences in reports with these people?
Are children useful for diagnosis/
What do you focus on when assessing ADHD?

A

Rating scales and interviews

  • Teacher report is crucial as we need to know about functioning at home and at school
  • Parents reports of symptoms/impairments at school is better correlated with their assessment for home than the teacher report for school (and vice versa)
  • Teachers also see many children so can place this vs. a normative standard
  • Situations at school press for hyperactivity/attention whereas at home the parents will adapt and not make the child who lacks concentration do tasks that require it

Do not ask youth, they underestimate their issues and it is not a reliable report. Good to check they understand though

Diagnostic interviews
Symptom rating scales
Focus is on OBSERVABLE signs of inattention and hyperactivity/impulsivity

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8
Q

An example of a diagnostic interview for ADHD is the

A

Kiddie SADS semi-structured interview

Many points to assess, involves clinical judgment by clinician

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9
Q

Combining reports from parents and teachers:

What diagnoses do you get with AND and OR rules?

A

When you look at parent or teacher alone, you see more ADHD-PI or ADHD-PH (possibly cos of different contexts).

Use the OR rule = many of these cases become ADHD-C

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10
Q

Neurophysiological diagnosis of ADHD

Is there a test?
What do you rule out first?

A

No blood test equivalent
But usually try to rule out biological factors that could cause inattention
Neuropsychological tests are not currently used in diagnosis but can provide information about symptoms or functioning that is not directly visible

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11
Q

Epidemiology of ADHD (Overview)

What is the point prevalence of ADHD?
What is the 6 month prevalence?
Lifetime prevalence?

A

Epidemiology of ADHD

  • Prevalence of ADHD
  • Point prevalence: 5-9% of school-age children in N. America
  • Ontario Child Health Study
  • 6-month prevalence: 10.5% of children aged 4-11 years
  • National Comorbidity Survey - Adolescents
  • Lifetime prevalence: 8.7%
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12
Q

Epidemiology of ADHD (Subtype differences by reporter)

A

Overall ADHD C 3.4%, HI 0.8%, PI 1.8%

Prevalence if diagnosis made using
“or” rule for symptoms to combine
parent and teacher report
C 5.1%, HI 2.1%, PI 6.7%

Prevalence if diagnosis made using
“and” rule for symptoms to combine
parent and teacher report
C 0.8%, HI 1.9%, PI 2.1%

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13
Q

Epidemiology of ADHD (Cultural and contextual differences)

A

Children in many cultures and countries meet diagnostic criteria for
ADHD
Slightly more prevalent among children living in poverty

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14
Q

Epidemiology of ADHD (Gender)

What ratios for each sex?
How do boys and girls typically present (what symptoms)?

A

3 boys:1 girl ratio in community
6 boys:1 girl ratio in clinics
Boys are sent to get treatment more. Could mean there are suffering girls who do not get treatment

Symptom presentation varies by gender
-In community samples, boys are more likely than are girls to be diagnosed with all subtypes of ADHD, but the gap is wider for ADHD-C and ADHD-HI than it is for ADHD-PI
-Girls more likely to be inattentive, drowsy, daydreamy, hyberverbal
-Boys more likely to display overt defiance and aggression
-May be more likely to be referred because of it
-Note that you do not see the same differences in presentation between boys and girls in
clinically referred samples (so maybe it is the oppositional ones that get referred as they are referred by parents dealing with this oppositional form

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15
Q

The developmental course of ADHD

A

Infancy:
-“Should” be present at birth. No idea if it is
-No reliable and valid measures to assess symptoms below three years of
age

Preschool:

  • Hyperactivity-impulsivity appears around 3 to 4 years of age
  • Often interferes with parent-child relationship
  • If symptoms last for about a year, child is likely to continue to have challenges

Elementary school:

  • Inattention becomes noticeable with cognitive demands of school
  • Start to see some decline in hyperactivity-impulsivity over the elementary school years

This means they get better but still have issues greater than that of non-ADHD kids

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16
Q

ADHD Prognosis

A

-Previously thought that symptoms of ADHD resolved in adolescence
-At least 5 prospective studies have shown that pre-adolescents who meet criteria for a diagnosis of ADHD have higher rates of ADHD symptoms in early adulthood (ages 21-27) compared to youth who do not have ADHD, after accounting for related
factors
-Approximately 1/3 of children diagnosed with ADHD will continue to meet criteria for a disorder in adulthood
-Who provides information about symptoms will change our understanding of the continuity
of the disorder
-Self reporters systematically understate their symptoms (just like they do in childhood)

17
Q

Adult Outcomes of ADHD

A
  • Between 1970 and 1978 recruited 207 boys who were referred to a no-cost clinic in New York State for behavior problems
  • To be included, participants had to be rated as hyperactive but not aggressive by a teacher AND a parent or a psychiatrist
  • Note that recruitment predates DSM-III which was when attention deficit disorder was first included
  • When the boys (probands) were 18, they recruited comparison participants
  • A comparison participant was recruited for each boy, matched for age and parental occupation
  • Control participants were deemed free of ADHD symptoms based on school records and parent report that there had never been teacher complaints about the participants’ behavior
  • Followed up with probands and comparisons when they were 41 years old
  • Attrition: 135 probands and 136 comparisons participated
  • Probands who participated did not differ from probands who were lost on childhood characteristics (e.g., SES), nor on rates of ADHD or substance use at age 25
  • Comparisons who participated tended to have higher SES and higher IQs (maybe a systematic difference)

RESULTS
Controls were more likely to finish high school, have a graduate degree, earn more, stay married, not be incarcerated and had a longer life expectancy vs probands with ADHD

18
Q

Correlates of ADHD (general categories)

4 Things

A
  • Comorbidity with other psychological disorders
  • Intellectual/academic impairment
  • Physical health problems
  • Social impairment
19
Q

Correlates of ADHD (Comorbidities with other psychological disorders)

4 General categories and their details

A

Up to 80% of children with ADHD have a co-occurring psychological disorder

  • Oppositional Defiant Disorder (ODD) and Conduct Disorder (CD)
  • 50% or more of children and adolescents with ADHD meet criteria for ODD
  • 30% to 50% will meet criteria for CD
  • Early-onset ADHD is a strong predictor of later CD and ODD
  • Anxiety disorders
  • 25-50% of children with ADHD experience excessive anxiety or an anxiety disorder
  • Depression
  • 20% to 30% of youth with ADHD will experience major depression
  • Tic Disorders
  • 20% of youth with ADHD meet criteria for tic disorder, characterized by sudden, repetitive movements or sounds such as eye blinking, facial grimacing, throat clearing, and grunting
20
Q

Correlates of ADHD (Academic)

Do they typically have lower intellect?
Do they test well?
Why?

A

Intellectual ability and academic functioning

  • ADHD is not associated with decreased intellectual ability
  • Academic functioning is impaired
  • Lower grades and scores on achievement tests (could be because school exams do not allow ADHD sufferers to show what they can do)
21
Q

Correlates of ADHD (Language issues)

Are there formal speech and language disorders?
What things commonly impact language for ADHD sufferers?

A

Formal speech and language disorders are present sometimes

Symptoms of ADHD impact language abilities

  • Excessive and loud talking
  • Frequent shifts and interruptions in conversation
  • Inability to listen (Shifting attention)
  • Speech production errors
22
Q

Correlates if ADHD (Interpersonal issues)

A

Interpersonal functioning
With family: Conflict with sibling and parents

With peers: Youth with ADHD are more disliked by classmates and have fewer friends than do youth without ADHD

23
Q

Etiology of ADHD

Heritability
Environmental factors

A

Heritability:
-Based on twin studies, heritability estimates for inattentive and hyperactive/impulsivity are approximately 75%

Environmental influences

  • Sugar does not cause hyperactivity
  • Factors that compromise development of nervous system may be related to ADHD
  • Maternal use of cigarettes, alcohol, and drugs while pregnant are associated with ADHD

It is difficult to disentangle substance use from other environmental factors such as low SES