Week 3 Flashcards
What is tinnitus?
This is a sensation of a sound when there is no auditory stimulus
What is vertigo?
Definitive illusion of movement of the subject , surroundings which indicates a disturbance of vestibular VIII CN brainstem or cortical function
What is Ménière’s disease ?
An excessive accumulation of endolymph in the membraneous labyrinth . The volume of endolymph increases with the distension of the Scala media untill the membrane ruptures
Clinical features of Ménière’s disease ?
Tinnitus
Fluctuating sensorineural hearing loss
Vertigo
Sensation of fullness in the ear
Treatment for Ménière’s disease ?
Symptomatic relief and surgical interventions
Symptomatic - during acute episodes with antiemetics and anticholinergics
Keeping a low sodium diet may help reduce vol of endolymph
Cessation of smoking
Surgical-
Shunts in place to drain excess endolymph
Removal of portions of the vestibulocochlear nerve and destruction of the membraneous labyrinth are option .
Explain tendon jerk reflexes
Stimulus - tendon tap stretches muscle and activates muscle spindle receptors then there is conduction along afferent sensory fibres .
Transmission at synapses between the afferent and motor neuron then there is conduction along the efferent motor fibres.
Neuromuscular transmission-> excitation contraction coupling -> twitch contraction of skeletal muscle
What are the three main divisions of the frontal lobe?
Prefrontal cortex - personality expression , complex cognitive behaviour
Premotor cortex - voluntary muscle movement
Primary motor cortex ( motor homunculus) - voluntary muscle movement
What cortex is in the parietal lobe?
Somatosensory cortex which is essential to the processing of the body’s senses . Pressure , touch , pain
The occipital lobe is the main centre for visual processing , what cortex is situated here?
Primary visual cortex.
This region of the brain receives visual input from the retina via the optic nerve and these visual signals are interpreted on the occipital lobes
What are the structures of the limbic system and what lobe are they in?
The olfactory cortex
Amygdala
Hippocampus
- all located in temporal lobe
What is wernicke’s area ?
Sensory language understanding , lexical processing .
Damage to here will result in aphasia and poor comprehension
What happens if there is damage to Broca’s area?
Results in aphasia , non fluent and slow speech because it is the motor aspect of speech
What is the primary auditory cortex?
Processing of auditory info
What parts is the basal ganglia divided into?
Corpus striatum
Subthalamic nuclei
Substantia Nigra
What is the corpus striatum made up of ?
Caudate nucleus
Putamen
Globus pallidus
What does the subthalamic nuclei produce?
The excitatory neurotransmitter glutamate
Substantia Nigra produces what?
The neurotransmitter dopamine which is involved in Nigro-striatal pathway. Damage to this causes Parkinson’s
What does the medulla oblongata do?
Deals with autonomic / involuntary functions . Carries out many life sustaining functions such as breathing , heart rate , blood pressure , swallowing
What does the pons connect?
Connects the cerebral cortex to the medulla
What is the thalamus ?
(Relay station)
It the location of the cell bodies of 3rd order neurons in ascending pathways