Embryology Flashcards
1
Q
Disruption in migration of neural crest cells can result in…
A
Treacher-Collins syndrome
Digeorge syndrome
2
Q
Digeorge syndrome
A
Cause by deletion of a small piece of chromosome 22
CATCH 22 - signs and symptoms
Cleft palate Abnormal face Thymic aplasia Cardiac abnormalities Hypocalcaemia / hypoparathyroidism
3
Q
Treacher Collins syndrome
A
Under development of zygomatic nine and ears
Mutation of TCOF 1 gene
4
Q
What is the mantle layer
A
A zone around the neuroepithelial that later forms the grey matter
5
Q
What happens if the anterior Neuropore fails to close by 25day
A
Anencephaly
6
Q
What happens if the posterior neuropore fails to close by day 28?
A
Spina bifida
7
Q
What is hydrocephalus
A
A build up of CSF in the brain - relieved by shunting fluid into the abdomen via surgical implantation. Of a shunt
