WEEK 3 Flashcards
Differentiation
Each cell types differentiates and carries out particular functions.
The structure reflects the function of the tissue.
Mitosis
Part of the cell cycle
Requires genetic control—DNA and RNA
Mutation
If DNA in parent cell is altered and passed on, offspring cells will carry the mutation
Apoptosis
Programmed cell death
Controlled by genetic elements
CANCER CELLS DONT HAVE THIS
SPREAD THOURGH LLYHMATIC SYSTEM OR THROUGH BLOOD VESSLES. VERY DISORGANIZED GROWTH. CANCER CELLS DON’T LOOK LIKE ORGINIAL CELL. SOME CANCER CELLS LOOK LIKE SOMETHING COMPLETELY DIFFERENT FROM THE ORGINAL CELL.
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Neoplasm or tumor
Cellular growth that no longer responds to normal genetic controls
Cell continues to reproduce, without need for them to reproduce
Deprives other cells of nutrition
Neoplasms may consist of atypical or immature cells.
Characteristics of each tumor depend on:
• Type of cell from which the tumor arises
• Unique structure and growth pattern
CANCER CELLS BRING BLOOD INTO THE MASS. WHICH CAN METASTASIZE INTO THE BLOOD
Defect in Cellular Proliferation
Most human tissues contain predetermined, undifferentiated stem cells.
Predetermined stem cells give rise to mature cells of the type of tissue where they reside.
OCULT BLOOD,- HIDDEN BLOOD.
MALINA STOOL- BLACK TAR STOOL.
TOP CANCER
MOST COMMON IN MEN
PROSTATE
LUNG
COLORECTAL
COMMON IN WOMEN
BREAST
LUNG
COLORECTAL
CANCER THAT KILLS THE MOST PEOPLE
LUNG CANCER. BECAUSE YOU TEST ONLY UNTIL AFTER MANIFESTATIONS
Defect in Cellular Proliferation
All cells are controlled by an intracellular mechanism that determines proliferation.
Cancer cells grown in culture are characterized by loss of contact inhibition.
—Grow on top of one another and on top of or between normal cells
Cancer cells respond differently from normal cells to intracellular signals regulating equilibrium.
—Divide indiscriminately
Stem cell theory
- –Loss of intracellular control of proliferation results from mutation of stem cells.
- –DNA is substituted or permanently rearranged.
Once mutated
- –Cells can die from damage or by initiating programmed cellular suicide (apoptosis).
- –Can recognize damage and repair itself
- –Surviving mutated cells have potential to become malignant.