week 3 Flashcards
young modulus
relationship bw stress and strain
represents elasticity
bone is strongest during
compression
Tension
If sufficient in magnitude & duration, may cause tendinosis or
inflammation of bone-tendon attachment
avulsion fracture’
- Portion of the bone torn away with ligament/tendon)
Bending
Walking & running creates large
bending force on femoral neck
several times greater than body
weight!
Tensile force on superior aspect,
compressive force on inferior aspect
Contraction of muscles gluteus
medius alters the stress distribution
Torsion
- Bone fails first in shear –
initial crack parallel to neutral
axis of bone - Second crack forms along
plane of maximal tensile
stress
Anisotrophy
describes tissues that respond differently depending on the direction of applied load.
Viscoelasticity
describes tissues that respond differently depending on the rate and duration of loading.
articular cartilage- 1. The superficial zone
the superficial zone is thin (10-20% volume) with the collagen fibres aligned parallel and close together on the surface. This zone is important for protecting the deeper layers and is responsible for resistance of tensile and shear loads.
articular cartilage- 2. The middle zone
The middle zone (40-60% volume) contains less chondrocytes, more PGs and thicker collagen fibrils, organized tangentially to the surface. The middle zone is the first line of defense against compressive loads.
articular cartilage- 3. The deep zone
The greatest resistance to compressive load is from the deep zone (30% volume) due to the arrangement of collagen fibrils perpendicular to the articular surface. The deep zone also has the largest diameter collagen, highest PG concentration and lowest water content.
Articular cartilage has high or low ability to repair?
limited capacity for repair & regeneration
Permeability
- Measure of the ease with which fluid can flow through a porous
material
Inversely proportional to the frictional drag exerted by fluid flowing
through porous material - Permeability low in articular cartilage
- Affected by magnitude of load
Fluid film lubrication
utilises a thin, viscous fluid-film that provides separation of the joint surfaces under less severe conditions when loads are low, oscillatory, and when the contacting surfaces are moving quickly
Boundary lubrication
utilises a specific glycoprotein, “lubricin” which forms a gel that prevents direct, surface-to-surface contact. Boundary lubrication is more important under severe loading conditions – high loads, long duration (and relatively low speeds)