Week 22: Hardy-Weinberg Flashcards

1
Q

Question on page 5

A
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2
Q

Question on page 7

A
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3
Q

Population:

A

a group of individuals of the same species living in the same (arbitrarily defined) area.

Members of a population are more likely to breed with each other than with members of another population

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4
Q

Gene pool:

A

all the alleles of all the genes in all individuals of a
population

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5
Q

Fixed allele:

A

when all individuals in a population are homozygous for one allele. No other alleles for that locus exist in the population.

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6
Q

Question on page 11

A
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7
Q

The frequency of a phenotype (i.e., a trait) =

A

Number of individuals with the phenotype / total number of all individuals

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8
Q

Question on page 13

A
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9
Q

Question on page 15

A
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10
Q

The frequency of an allele in a population =

Equation:

page 17 for visuals*

A

its proportion in a population

number of copies of allele / total number of all copies of all alleles for that gene

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11
Q

Question on page 18

A
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12
Q

If a population’s expected frequencies match its observed frequencies, and this does not change, then the population is at ______________

A

equilibrium

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13
Q

The Hardy-Weinberg assumes what is not occuring

A
  1. Natural selection
  2. Genetic drift
  3. Gene flow
  4. Non-random mating
  5. Mutation
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14
Q

The Hardy Weinberg equation:

A

Let p = frequency (proportion) of the dominant allele

Let q = frequency (proportion) of the recessive allele

p + q = 1

therefore

p^2 + 2pq + q^2 = 1

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15
Q

Question on page 23

A
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16
Q

The Rule of Multiplication

Explanation on page 25

A
17
Q

There are TWO WAYS an individual could inherit one dominant and one recessive allele:

A
  1. A sperm carrying a dominant allele (frequency = p) could fertilize an ovum carrying a recessive allele (frequency = q); odds = p*q (Aa)
  2. A sperm carrying a recessive allele (frequency = q) could fertilize an ovum carrying a dominant allele (frequency = p); odds = q*p (aA) = Aa
18
Q

The Rule of Addition:

A

The probability of an event that can occur in two or more different ways is equal to the sum of the individual probabilities of each way

Odds of being a heterozygote are therefore
(p * q) + (q * p) = 2pq

19
Q

The HW equation only applies to populations that are ……

A

NOT evolving

20
Q

Question on page 32

A
21
Q

Question on page 34

A

c) 0.04

q^2= aa

0.2 x 0.2 = 0.04

22
Q

Question on page 36

A

e) 96%

p^2 + 2pq = AA

(0.8)^2 + 2(0.8)(0.2) = 0.96

0.96 x 100 = 96%

23
Q

Causes of evolution:

A
  1. Natural selection
  2. Genetic drift
  3. Gene flow
  4. Non-random mating
  5. Mutation
24
Q

why does the Hardy weinberg equation no longer predict genotype frequencies accurately when natural selection acts against a trait

A

When natural selection acts against a particular trait, it disrupts the balance described by the Hardy-Weinberg equilibrium. Natural selection favors certain alleles over others, leading to changes in allele frequencies within the population.

If a trait is under negative selection (disadvantageous), individuals with the corresponding genotype will have reduced fitness and are less likely to survive and reproduce. As a result, the frequency of that genotype will decrease over time, disrupting the equilibrium predicted by the Hardy-Weinberg equation.

25
Q

Review slide 43-46

A
26
Q

Huntington’s disease

A

A disorder of the nervous system.

27
Q

Huntington’s disease - when do symptoms begin to appear? When do they become fatal?

A

Symptoms usually begin to appear between the ages of 35 and 45

Fatal within 15-20 years of the onset of symptoms.

28
Q

Huntington’s disease associated with dominant or recessive allele

A

Huntington’s disease associated with dominant allele

29
Q

Practice question page 56 - 58

Review lab 6 quiz and Quiz 6 on eclass for practice

A
30
Q

Which is true of populations that are in Hardy-Weinberg equilibrium?

Question 2 Select one:

a.
Natural selection is occurring.

b.
The populations must be very small.

c.
Mating is random.

d.
Organisms are constantly migrating.

e.
All of the above are true.

A

c. Mating is random

31
Q

Why is the concept of Hardy-Weinberg Equilibrium useful in evolution?

a.
When predicted genotypic frequencies match observed genotypic frequencies, we can accurately predict which genotypes are advantageous.

b.
When predicted genotypic frequencies match observed genotypic frequencies, we can assume that evolution is occurring at a steady rate.

c.
When predicted genotypic frequencies match observed genotypic frequencies, we can assume that the population is not evolving.

d.
When predicted genotypic frequencies match observed genotypic frequencies, we can accurately determine which alleles were under selection in the past.

e.
When predicted genotypic frequencies match observed genotypic frequencies, we can say that evolution is definitely occurring.

A

c.
When predicted genotypic frequencies match observed genotypic frequencies, we can assume that the population is not evolving.

32
Q

Natural Selection acts on:

Select one:

a.
Genotypes

b.
Phenotypes

c.
Individuals

d.
Both A and C

e.
Both B and C

A

e.
Both B and C

33
Q

Frogs are particularly vulnerable to an invasive pathogen called chytridiomycosis (chytrid fungus). When chytrid fungus is introduced to new populations, the disease can kill nearly all the individuals. However, those few individuals who escape the disease have some degree of resistance to the fungus.

True or False: this scenario represents a beneficial bottleneck event, leading to higher reproduction and fitness for those individuals that survive the bottleneck.

Select one:
True
False

A

True